Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2319356..2319627 Replicon chromosome
Accession NZ_CP086616
Organism Escherichia coli strain RIVM_C039629

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2319486..2319589 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2319356..2319627 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN353_RS11160 2315911..2316573 - 663 WP_000944256.1 exodeoxyribonuclease X -
LN353_RS11165 2316597..2317253 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LN353_RS11170 2317355..2317585 - 231 WP_000916760.1 DNA polymerase III subunit theta -
LN353_RS11175 2317724..2318098 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LN353_RS11180 2318102..2318974 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
LN353_RS11185 2318987..2319328 + 342 WP_000976472.1 YebY family protein -
- 2319356..2319627 - 272 - - Antitoxin
- 2319486..2319589 + 104 - - Toxin
LN353_RS11190 2319724..2320380 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
LN353_RS11195 2320381..2320572 - 192 WP_001296140.1 YebW family protein -
LN353_RS11200 2320677..2320913 - 237 WP_001295499.1 YebV family protein -
LN353_RS11205 2321031..2322470 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2310183..2335467 25284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224029 NZ_CP086616:2319486-2319589 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224029 NZ_CP086616:c2319627-2319356 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References