Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2025115..2025386 Replicon chromosome
Accession NZ_CP086538
Organism Escherichia coli strain Ec-042-T5-MAC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2025245..2025348 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2025115..2025386 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN52_RS09755 2021670..2022332 - 663 WP_000944256.1 exodeoxyribonuclease X -
LNN52_RS09760 2022356..2023012 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LNN52_RS09765 2023114..2023344 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LNN52_RS09770 2023483..2023857 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LNN52_RS09775 2023861..2024733 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LNN52_RS09780 2024746..2025087 + 342 WP_000976492.1 YebY family protein -
- 2025115..2025386 - 272 - - Antitoxin
- 2025245..2025348 + 104 - - Toxin
LNN52_RS09785 2025483..2026139 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LNN52_RS09790 2026140..2026331 - 192 WP_001296140.1 YebW family protein -
LNN52_RS09795 2026436..2026672 - 237 WP_001295499.1 YebV family protein -
LNN52_RS09800 2026790..2028229 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T223748 NZ_CP086538:2025245-2025348 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT223748 NZ_CP086538:c2025386-2025115 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References