Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2144288..2144559 Replicon chromosome
Accession NZ_CP086500
Organism Escherichia coli strain Ec-050-T5-MAC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2144418..2144521 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2144288..2144559 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN49_RS10255 2140843..2141505 - 663 WP_000944256.1 exodeoxyribonuclease X -
LNN49_RS10260 2141529..2142185 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LNN49_RS10265 2142287..2142517 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LNN49_RS10270 2142656..2143030 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LNN49_RS10275 2143034..2143906 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
LNN49_RS10280 2143919..2144260 + 342 WP_000976476.1 YebY family protein -
- 2144288..2144559 - 272 - - Antitoxin
- 2144418..2144521 + 104 - - Toxin
LNN49_RS10285 2144656..2145312 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LNN49_RS10290 2145313..2145504 - 192 WP_000457842.1 YebW family protein -
LNN49_RS10295 2145609..2145845 - 237 WP_001295499.1 YebV family protein -
LNN49_RS10300 2145963..2147402 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T223586 NZ_CP086500:2144418-2144521 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT223586 NZ_CP086500:c2144559-2144288 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References