Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-vagC/VapC-VagC
Location 153102..153739 Replicon chromosome
Accession NZ_CP086291
Organism Burkholderia ambifaria strain B21-008

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LL999_RS00685 Protein ID WP_105831291.1
Coordinates 153338..153739 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag LL999_RS00680 Protein ID WP_126228768.1
Coordinates 153102..153338 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL999_RS00660 (LL999_00660) 149096..150190 - 1095 WP_229061261.1 ADP-heptose--LPS heptosyltransferase -
LL999_RS00665 (LL999_00665) 150187..151890 - 1704 WP_229061263.1 thiamine pyrophosphate-binding protein -
LL999_RS00670 (LL999_00670) 152186..152647 + 462 WP_229061265.1 hypothetical protein -
LL999_RS00675 (LL999_00675) 152644..152928 + 285 WP_105831290.1 type II toxin-antitoxin system RelE/ParE family toxin -
LL999_RS00680 (LL999_00680) 153102..153338 + 237 WP_126228768.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LL999_RS00685 (LL999_00685) 153338..153739 + 402 WP_105831291.1 type II toxin-antitoxin system VapC family toxin Toxin
LL999_RS00690 (LL999_00690) 153807..155195 - 1389 WP_105831292.1 L-serine ammonia-lyase -
LL999_RS00695 (LL999_00695) 155226..156362 - 1137 WP_229061267.1 alginate lyase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15087.27 Da        Isoelectric Point: 5.6577

>T222918 WP_105831291.1 NZ_CP086291:153338-153739 [Burkholderia ambifaria]
MPRYMLDTNMCIYLMKNQPEQVARRFAQCYTGDVVMSAITYAELEYGVTVCANPARERRHLAALIDDIPVAPFDVAAAQA
YGPVREATRERKKDHLDKLIAAHAVSLDVVLVTNNERDFVSYPGLRLENWLND

Download         Length: 402 bp

>T222918 NZ_CP118155:543032-543214 [Pseudomonas chlororaphis]
ATGCGCAGTCGGGAACTGATCAGGATGATCGAGGAGGACGGGTGGTATCTGATCGCGGTCAAAGGCAGTCATCACCAGTA
CAAGCATCTGCACAAGCCGGGGCGGGTCACTATCCCTCACCCGGATGCGGATCTGCCCAGGGGCACGATCCACAGCATCT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8982.04 Da        Isoelectric Point: 5.1473

>AT222918 WP_126228768.1 NZ_CP086291:153102-153338 [Burkholderia ambifaria]
MHTTRVFRNGNSQAVRIPADLAYERSDIELEIERVGDEIRIRPTRQPLTHVLEKFAKFGPDFMAEGRGDQEQADREGL

Download         Length: 237 bp

>AT222918 NZ_CP118155:543244-543645 [Pseudomonas chlororaphis]
ATGAAATTCCCGGTCGTGCTGCACAAGGATGCCGACTCCGGATATGGAGTGATCGTCCCCGATGTGCCGGGCTGTTTTTC
CGCCGGTCATACCGCTGCGCAAGCCTTCGAGAATGTGAAAGAAGCCTTGTCGCTGCACTACGAAGGCCTGGTCGCCGATG
GTGAGCCGCTGCCCCAGGTACATGAGGTTGATGTGCATATCGACAATCCCGATTACGCCGGCGGTGTATGGGGGGTGGTC
GATTTCGATATCACGCCTTACTTCGGCAAGGCGGTGCGTTTTAATGCGACGTTGCCGGAGCAACTGTTGGAGCGCATCGA
CCAGACAGTGAAGCGCGACCAGCGCTACCGTTCGCGCTCGGGTTTTCTCGCCGCGGCGGCACTACGCGAGCTCTCCGCCT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References