Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3733530..3735049 Replicon chromosome
Accession NZ_CP086180
Organism Xanthomonas oryzae strain PXO363

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL927_RS17825 Protein ID WP_011259680.1
Coordinates 3734126..3735049 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL927_RS17820 Protein ID WP_011409027.1
Coordinates 3733530..3734129 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL927_RS17785 (LL927_17750) 3729212..3729748 - 537 WP_011409032.1 lipocalin family protein -
LL927_RS17795 (LL927_17760) 3730018..3730485 - 468 WP_181718264.1 hypothetical protein -
LL927_RS17800 (LL927_17765) 3730466..3730756 - 291 WP_011409031.1 hypothetical protein -
LL927_RS17805 (LL927_17770) 3731255..3732286 + 1032 WP_042465093.1 IS630 family transposase -
LL927_RS17810 (LL927_17775) 3732268..3732843 - 576 WP_011409029.1 BrxE family protein -
LL927_RS17815 (LL927_17780) 3732875..3733165 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
LL927_RS17820 (LL927_17785) 3733530..3734129 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL927_RS17825 (LL927_17790) 3734126..3735049 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL927_RS17830 (LL927_17795) 3735129..3735599 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LL927_RS17835 (LL927_17800) 3736065..3736307 + 243 WP_011409025.1 hypothetical protein -
LL927_RS17840 (LL927_17805) 3736759..3737724 - 966 Protein_3407 IS1595-like element ISXo5 family transposase -
LL927_RS17845 (LL927_17810) 3737819..3738307 + 489 WP_069959937.1 hypothetical protein -
LL927_RS17850 (LL927_17815) 3738324..3738856 - 533 Protein_3409 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222656 WP_011259680.1 NZ_CP086180:3734126-3735049 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222656 NZ_CP117993:c941928-941629 [Enterobacter hormaechei]
ATGATTAATCATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTCTACGGGAGATCGAGCAATGTTATTCCTTTGAATCT
GGAAACAGCGCTTGCAAGAAAGCTCGACATCATCAATGCGGCCATGTCGCACCTGGATTTACGATCGCCACCGGGCAATA
TGTATGAAGCATTGAGTCCTCCGTTGAAGGGATATTCCTCTATCCGGGTAAACAGACAATACAGGCTTGTATTTCGCTGG
TCAGAGGGAAAAGCAGACGATCTCTATCTCTCTCCAAACAAGTACACGCAACACAAGTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222656 WP_011409027.1 NZ_CP086180:3733530-3734129 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222656 NZ_CP117993:c941618-941253 [Enterobacter hormaechei]
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGAGGTGTTGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAACGATCTGGCAGAGATGCTAAATGTACACCGCAATACCGTAAGCGCGTTGGTCAATAACAATCGCAAACTTA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTAATACCACTATTGAATTTTGGCTGAACTTACAGCTAAACGTTGAT
ATCTGGGAAGCGCAATCTAACTCCCGCACGCAGGAGGAGTTAAGCCGGATAAAAACCGTTGCGGAAGTCATGGCGAAGCG
AAAATCCGGCAAGCCAGACGTTACCCTGCACGGGAACAGCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References