Detailed information of TA system TA222230

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3426583..3427045
• Replicon: chromosome
• Accession: NZ_CP085885
• Organism: Pseudomonas sp. HN2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LIS66_RS14835
• Protein ID: WP_252876246.1
• Coordinates: 3426815..3427045 (+)
• Length: 77 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LIS66_RS14830
• Protein ID: WP_227972457.1
• Coordinates: 3426583..3426777 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LIS66_RS14800 (LIS66_14800)	3421814..3422641	+	828	WP_227972454.1	ABC transporter permease	-
LIS66_RS14805 (LIS66_14805)	3422638..3423405	+	768	WP_227972455.1	phosphonate ABC transporter, permease protein PhnE	-
LIS66_RS14810 (LIS66_14810)	3423584..3425263	+	1680	WP_042606823.1	MFS transporter	-
LIS66_RS14815 (LIS66_14815)	3425372..3425590	+	219	WP_042606898.1	hypothetical protein	-
LIS66_RS14820 (LIS66_14820)	3425822..3426016	+	195	WP_116657815.1	stability determinant	-
LIS66_RS14825 (LIS66_14825)	3425979..3426290	+	312	WP_227972456.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LIS66_RS14830 (LIS66_14830)	3426583..3426777	+	195	WP_227972457.1	stability determinant	Antitoxin
LIS66_RS14835 (LIS66_14835)	3426815..3427045	+	231	WP_252876246.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-71)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 77 a.a.
• Molecular weight: 8776.17 Da
• Isoelectric Point: 10.5885

>T222230 WP_252876246.1 NZ_CP085885:3426815-3427045 [Pseudomonas sp. HN2]
IEYVEQRNTVASLALHQKLSAAARRLSWIPHGFRSGRIPGTREMVINSNYLLVYRVTDQINILTVLHALKKYPYHS

Nucleotide

• Length: 231 bp

>T222230 NZ_CP117726:32024-32275 [Enterobacter asburiae]
ATGAGAAAAAATAAAGGTGATGTGACTTATTTTCTTGAAAAAGAAGGTGACAATTACAGGCTTACAAAAAGGATAAAAGC
CAGAACAAATGTTAAAATCGGGAACAAAACTACGAAAATTACATTGTATGATGCTGTACTGAATGAGAATGAATTACAAC
ATATTGATTTTACGTGTGCCGGATTAAGGGAAGACGATGAGACGCCAGTTAAGAATTTAATTAAGGAGTTTATGTTAAAT
GAAACCCGATAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7315.20 Da
• Isoelectric Point: 4.5822

>AT222230 WP_227972457.1 NZ_CP085885:3426583-3426777 [Pseudomonas sp. HN2]
MSAELSPIVSDFETEEEAASYDRWYRAKVQAALDEPRPPVPHDEAMVLLGQMLEERRKNRRAAG

Nucleotide

• Length: 195 bp

>AT222230 NZ_CP117726:32262-32489 [Enterobacter asburiae]
ATGAAACCCGATAATACACCTGAAAATGTAAAAAAATTACGTTTAAAAGCAGGATTAACACAAAAGGAATGCAGTCATAT
TTATGGTGTTGGGCTAAGAACCTGGCAGAAAAAAGAGGAAGTTAATACTCAAAACAGTCAAAGTCTGTCACTGGTTGAGT
TTGAGTTTCTTTTGTTACTTGCAGGAGAACATCCTGAATACGTGCTCTGCAAAAGGGAGTCAAAATAA