Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1400724..1400869 Replicon chromosome
Accession NZ_CP085729
Organism Klebsiella pneumoniae strain 59062CZ

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1400731..1400833 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1400724..1400869 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJU45_RS07255 (LJU45_07255) 1396256..1397689 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LJU45_RS07260 (LJU45_07260) 1397805..1398044 + 240 WP_002911393.1 YebV family protein -
LJU45_RS07265 (LJU45_07265) 1398142..1398333 + 192 WP_002911395.1 YebW family protein -
LJU45_RS07270 (LJU45_07270) 1398330..1398983 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
LJU45_RS07275 (LJU45_07275) 1399140..1400108 + 969 WP_004151446.1 VirK/YbjX family protein -
LJU45_RS07280 (LJU45_07280) 1400213..1400356 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1400724..1400869 + 146 - - Antitoxin
- 1400731..1400833 - 103 - - Toxin
LJU45_RS07285 (LJU45_07285) 1400992..1401330 - 339 WP_002911404.1 YebY family protein -
LJU45_RS07290 (LJU45_07290) 1401347..1402216 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LJU45_RS07295 (LJU45_07295) 1402220..1402594 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LJU45_RS07300 (LJU45_07300) 1402707..1402937 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LJU45_RS07305 (LJU45_07305) 1403016..1403675 + 660 WP_002911407.1 exodeoxyribonuclease X -
LJU45_RS07310 (LJU45_07310) 1403679..1405739 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T221124 NZ_CP085729:c1400833-1400731 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT221124 NZ_CP085729:1400724-1400869 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References