Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 6348146..6348657 Replicon chromosome
Accession NZ_CP085636
Organism Shewanella sp. MTB7

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HWQ47_RS27845 Protein ID WP_269969164.1
Coordinates 6348146..6348406 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HWQ47_RS27850 Protein ID WP_269969165.1
Coordinates 6348406..6348657 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWQ47_RS27825 (HWQ47_27830) 6344143..6344784 - 642 WP_269969161.1 LysE family translocator -
HWQ47_RS27830 6345403..6345534 + 132 WP_269969162.1 hypothetical protein -
HWQ47_RS27835 (HWQ47_27835) 6345608..6346789 + 1182 WP_269971878.1 crosslink repair DNA glycosylase YcaQ family protein -
HWQ47_RS27840 6347185..6348135 + 951 WP_269969163.1 DUF1186 domain-containing protein -
HWQ47_RS27845 (HWQ47_27850) 6348146..6348406 - 261 WP_269969164.1 Txe/YoeB family addiction module toxin Toxin
HWQ47_RS27850 (HWQ47_27855) 6348406..6348657 - 252 WP_269969165.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HWQ47_RS27855 (HWQ47_27860) 6349234..6350214 - 981 WP_269969166.1 transposase -
HWQ47_RS27860 (HWQ47_27865) 6350288..6350980 - 693 WP_269969167.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10451.92 Da        Isoelectric Point: 9.8837

>T221000 WP_269969164.1 NZ_CP085636:c6348406-6348146 [Shewanella sp. MTB7]
MNILFSDNAWNDYLYWQQQDKKTLKRINLLIKDCQRTPFEGIGKPERLKENLSGYWSRRITDEHRLVYKATQDRLTIVAL
RYHYSS

Download         Length: 261 bp

>T221000 NZ_CP117327:c993999-993472 [Salmonella enterica subsp. enterica serovar Saintpaul]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCGGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTACTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9495.61 Da        Isoelectric Point: 4.4607

>AT221000 WP_269969165.1 NZ_CP085636:c6348657-6348406 [Shewanella sp. MTB7]
MSVYSFTEVRSNFKSVCDSVVNDCEPAVIHRRGAENVVMFSESEFNSWKETIYLLSNPVNAKHLLDSIKQVEEGQAQERE
LLD

Download         Length: 252 bp

>AT221000 NZ_CP117327:c994286-993996 [Salmonella enterica subsp. enterica serovar Saintpaul]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACATACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTAAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References