Detailed information of TA system TA022098

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 3603327..3604274
• Replicon: chromosome
• Accession: NC_009483
• Organism: Geobacter uraniireducens Rf4

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: GURA_RS24710
• Protein ID: WP_198134567.1
• Coordinates: 3603933..3604274 (+)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: GURA_RS15690
• Protein ID: WP_041246057.1
• Coordinates: 3603327..3603923 (+)
• Length: 199 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GURA_RS24705	3600778..3600942	-	165	WP_198134479.1	hypothetical protein	-
GURA_RS15685	3601872..3603197	+	1326	WP_049818937.1	site-specific integrase	-
GURA_RS15690	3603327..3603923	+	597	WP_041246057.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
GURA_RS24710	3603933..3604274	+	342	WP_198134567.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
GURA_RS24715	3604216..3604854	+	639	WP_198134480.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
GURA_RS15700	3604898..3605368	+	471	WP_041245500.1	hypothetical protein	-
GURA_RS15705	3605347..3606252	+	906	Protein_3158	site-specific integrase	-
GURA_RS15710	3606520..3607630	+	1111	Protein_3159	IS4 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (34-108)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-51)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12921.95 Da
• Isoelectric Point: 8.5455

>T22098 WP_198134567.1 NC_009483:3603933-3604274 [Geobacter uraniireducens Rf4]
IRLTFPLPCGNVLNRSKGQGEDFQLVLTRFVLERLLYRLGRSQFREQFILKGAMLFSLWGDTPHRATRDIDFLGFGESAV
NRLVQIFQAVCLTRVEEDGVIFLQESVRGMGNT

Nucleotide

• Length: 342 bp

>T22098 NC_009483:3603933-3604274 [Geobacter uraniireducens Rf4]
ATCCGTCTGACATTTCCGCTTCCGTGCGGCAACGTCCTAAATAGATCCAAGGGGCAAGGCGAAGATTTCCAGCTTGTCCT
TACCCGTTTCGTCCTGGAAAGACTCCTTTACCGTCTAGGCCGTTCCCAGTTCCGAGAACAGTTCATTCTCAAGGGGGCCA
TGCTCTTTTCCCTGTGGGGCGACACACCTCACCGCGCCACACGCGACATTGACTTTCTCGGCTTTGGAGAAAGTGCAGTT
AACCGGCTTGTACAGATTTTTCAAGCCGTATGCCTGACTCGGGTTGAAGAGGACGGAGTCATTTTCCTTCAGGAAAGCGT
CAGGGGTATGGGAAATACGTGA

Antitoxin

Protein

• Length: 199 a.a.
• Molecular weight: 22722.66 Da
• Isoelectric Point: 9.5872

>AT22098 WP_041246057.1 NC_009483:3603327-3603923 [Geobacter uraniireducens Rf4]
ISPIEKIISLAKEGGIIRPRDLDAYGIPREYLRRLSVKGILERQSRGIYTLHEVELTQHHSLMQACKRLPKGVVCLLSAL
RYHGLTTQAPFEIWMAIDRKARLPKVEGVPLHLVRFSGEALTEGIERHRIEGVDVSVYCPAKTVADCFKYRNKIGLDVAL
EALRECRRERRCTMDDLWRYAKICRVANVIRPYLEALS

Nucleotide

• Length: 597 bp

>AT22098 NC_009483:3603327-3603923 [Geobacter uraniireducens Rf4]
ATTTCACCGATAGAAAAAATAATCAGCCTTGCCAAGGAAGGGGGCATCATCCGTCCCCGTGATCTGGATGCATATGGCAT
CCCCAGGGAATACCTGCGCCGCCTTAGTGTCAAGGGAATCCTGGAGCGCCAGTCCCGCGGCATCTATACCCTTCATGAGG
TCGAACTGACCCAGCATCACAGCCTGATGCAGGCATGCAAGCGGCTGCCGAAAGGGGTGGTCTGTCTCCTCTCCGCGCTC
CGCTATCATGGTCTCACCACCCAGGCACCCTTTGAGATCTGGATGGCCATTGACCGCAAGGCACGGCTTCCCAAGGTGGA
AGGGGTGCCGCTTCATCTCGTCCGTTTTTCCGGTGAGGCCCTCACTGAAGGAATCGAGCGCCATCGGATCGAAGGTGTGG
ACGTGAGTGTCTATTGTCCGGCCAAGACCGTCGCCGACTGCTTCAAATACCGTAACAAGATCGGGCTGGATGTGGCACTC
GAGGCCCTGCGCGAATGTCGGCGCGAGCGCCGCTGCACCATGGACGATCTTTGGCGCTATGCAAAGATCTGCCGGGTGGC
AAACGTCATACGCCCCTACCTGGAGGCTCTTTCGTGA