Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2058003..2058148 Replicon chromosome
Accession NZ_CP084866
Organism Klebsiella pneumoniae strain SA12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2058039..2058141 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2058003..2058148 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM09_RS09900 2053133..2055193 + 2061 WP_004151449.1 oligopeptidase B -
LGM09_RS09905 2055197..2055856 - 660 WP_002911407.1 exodeoxyribonuclease X -
LGM09_RS09910 2055935..2056165 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM09_RS09915 2056278..2056652 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM09_RS09920 2056656..2057525 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
LGM09_RS09925 2057542..2057880 + 339 WP_002911404.1 YebY family protein -
- 2058003..2058148 - 146 - - Antitoxin
- 2058039..2058141 + 103 - - Toxin
LGM09_RS09930 2058516..2058659 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LGM09_RS09935 2058764..2059732 - 969 WP_014907334.1 VirK/YbjX family protein -
LGM09_RS09940 2059889..2060542 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LGM09_RS09945 2060539..2060730 - 192 WP_002911395.1 YebW family protein -
LGM09_RS09950 2060828..2061067 - 240 WP_002911393.1 YebV family protein -
LGM09_RS09955 2061183..2062616 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219636 NZ_CP084866:2058039-2058141 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219636 NZ_CP084866:c2058148-2058003 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References