Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4126559..4126704 Replicon chromosome
Accession NZ_CP084823
Organism Klebsiella pneumoniae strain T69

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4126566..4126668 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4126559..4126704 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM19_RS20100 4122091..4123524 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LGM19_RS20105 4123640..4123879 + 240 WP_002911393.1 YebV family protein -
LGM19_RS20110 4123977..4124168 + 192 WP_002911395.1 YebW family protein -
LGM19_RS20115 4124165..4124818 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
LGM19_RS20120 4124975..4125943 + 969 WP_004151446.1 VirK/YbjX family protein -
LGM19_RS20125 4126048..4126191 + 144 WP_032458836.1 Ecr family regulatory small membrane protein -
- 4126559..4126704 + 146 - - Antitoxin
- 4126566..4126668 - 103 - - Toxin
LGM19_RS20130 4126827..4127165 - 339 WP_002911404.1 YebY family protein -
LGM19_RS20135 4127182..4128051 - 870 WP_004899136.1 copper homeostasis membrane protein CopD -
LGM19_RS20140 4128055..4128429 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LGM19_RS20145 4128542..4128772 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LGM19_RS20150 4128851..4129510 + 660 WP_002911407.1 exodeoxyribonuclease X -
LGM19_RS20155 4129514..4131574 - 2061 WP_004899137.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T219463 NZ_CP084823:c4126668-4126566 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT219463 NZ_CP084823:4126559-4126704 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References