Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1900396..1901314 Replicon chromosome
Accession NZ_CP084643
Organism Yersinia ruckeri strain 17Y0159

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LGL91_RS08500 Protein ID WP_234056461.1
Coordinates 1900856..1901314 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag LGL91_RS08495 Protein ID WP_038242631.1
Coordinates 1900396..1900842 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL91_RS08475 (LGL91_08490) 1896094..1896798 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LGL91_RS08480 (LGL91_08495) 1896809..1897783 - 975 WP_234056460.1 L-Ala-D/L-Glu epimerase -
LGL91_RS08485 (LGL91_08500) 1897933..1898436 + 504 WP_004717547.1 thiol peroxidase -
LGL91_RS08490 (LGL91_08505) 1898471..1900078 - 1608 WP_038251390.1 transcriptional regulator TyrR -
LGL91_RS08495 (LGL91_08510) 1900396..1900842 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
LGL91_RS08500 (LGL91_08515) 1900856..1901314 + 459 WP_234056461.1 RES domain-containing protein Toxin
LGL91_RS08505 (LGL91_08520) 1901318..1902376 - 1059 WP_038242635.1 YcjF family protein -
LGL91_RS08510 (LGL91_08525) 1902373..1903770 - 1398 WP_234056462.1 YcjX family protein -
LGL91_RS08515 (LGL91_08535) 1904057..1904416 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LGL91_RS08520 (LGL91_08540) 1904416..1904643 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
LGL91_RS08525 (LGL91_08545) 1904727..1905392 - 666 WP_145497062.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17067.54 Da        Isoelectric Point: 6.7537

>T218978 WP_234056461.1 NZ_CP084643:1900856-1901314 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSASSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSIHPLTFSFDPRLK

Download         Length: 459 bp

>T218978 NZ_CP116145:c4956595-4956488 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT218978 WP_038242631.1 NZ_CP084643:1900396-1900842 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp

>AT218978 NZ_CP116145:4956643-4956709 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References