Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacT-ataR/DUF1778(antitoxin) |
Location | 5542041..5542801 | Replicon | chromosome |
Accession | NZ_CP083951 | ||
Organism | Mesorhizobium sp. B2-8-5 |
Toxin (Protein)
Gene name | tacT | Uniprot ID | - |
Locus tag | FJ430_RS27500 | Protein ID | WP_140705463.1 |
Coordinates | 5542322..5542801 (+) | Length | 160 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | - |
Locus tag | FJ430_RS27495 | Protein ID | WP_140705465.1 |
Coordinates | 5542041..5542322 (+) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FJ430_RS27475 (FJ430_27475) | 5538842..5539072 | + | 231 | WP_140705470.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
FJ430_RS27480 (FJ430_27480) | 5539083..5539565 | - | 483 | WP_140705469.1 | transcription elongation factor GreA | - |
FJ430_RS27485 (FJ430_27485) | 5539670..5541046 | + | 1377 | WP_140705467.1 | TIGR03808 family TAT-translocated repetitive protein | - |
FJ430_RS27490 (FJ430_27490) | 5541043..5541855 | - | 813 | WP_140705538.1 | methyltransferase domain-containing protein | - |
FJ430_RS27495 (FJ430_27495) | 5542041..5542322 | + | 282 | WP_140705465.1 | DUF1778 domain-containing protein | Antitoxin |
FJ430_RS27500 (FJ430_27500) | 5542322..5542801 | + | 480 | WP_140705463.1 | GNAT family N-acetyltransferase | Toxin |
FJ430_RS27505 (FJ430_27505) | 5542794..5543798 | - | 1005 | WP_140705461.1 | asparaginase | - |
FJ430_RS27510 (FJ430_27510) | 5543851..5545017 | - | 1167 | WP_140705459.1 | acetyl-CoA acetyltransferase | - |
FJ430_RS27515 (FJ430_27515) | 5545206..5545796 | + | 591 | WP_140705457.1 | transcriptional regulator BetI | - |
FJ430_RS27520 (FJ430_27520) | 5545793..5547322 | + | 1530 | WP_140705455.1 | choline-sulfatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 160 a.a. Molecular weight: 16953.42 Da Isoelectric Point: 8.8983
>T217847 WP_140705463.1 NZ_CP083951:5542322-5542801 [Mesorhizobium sp. B2-8-5]
MLSAPVLLADSHELDFFQSGTDSLDQWLRRRARANQVSGASRTYVIAEGTRVVGYYCLSSGGLDLVDAPGSIRRNMPDPV
PMAVLGRLAVDAGRQGKGLGVALLQDAVLRTGQAAAILGIRGLLVHAISDEAKAFYEHYGFQASPKNPMTLVLSLRTAS
MLSAPVLLADSHELDFFQSGTDSLDQWLRRRARANQVSGASRTYVIAEGTRVVGYYCLSSGGLDLVDAPGSIRRNMPDPV
PMAVLGRLAVDAGRQGKGLGVALLQDAVLRTGQAAAILGIRGLLVHAISDEAKAFYEHYGFQASPKNPMTLVLSLRTAS
Download Length: 480 bp
>T217847 NZ_CP114891:3126420-3126698 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10709.18 Da Isoelectric Point: 8.5141
>AT217847 WP_140705465.1 NZ_CP083951:5542041-5542322 [Mesorhizobium sp. B2-8-5]
MATKNQDRHAKPVNLRIREDVRILIDRAAKIRGKTRSDFMIDAAYRAAEDTLLDQTLVKVDAESYQHYLDILDQPPSGEG
FARLMNAPKPWRD
MATKNQDRHAKPVNLRIREDVRILIDRAAKIRGKTRSDFMIDAAYRAAEDTLLDQTLVKVDAESYQHYLDILDQPPSGEG
FARLMNAPKPWRD
Download Length: 282 bp
>AT217847 NZ_CP114891:3126157-3126417 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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