Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2039813..2039958 Replicon chromosome
Accession NZ_CP083932
Organism Klebsiella pneumoniae strain BA4946

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2039849..2039951 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2039813..2039958 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCH45_RS09910 2034943..2037003 + 2061 WP_004151449.1 oligopeptidase B -
LCH45_RS09915 2037007..2037666 - 660 WP_043906809.1 exodeoxyribonuclease X -
LCH45_RS09920 2037745..2037975 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LCH45_RS09925 2038088..2038462 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LCH45_RS09930 2038466..2039335 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LCH45_RS09935 2039352..2039690 + 339 WP_002911404.1 YebY family protein -
- 2039813..2039958 - 146 - - Antitoxin
- 2039849..2039951 + 103 - - Toxin
LCH45_RS09940 2040327..2040470 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LCH45_RS09945 2040575..2041543 - 969 WP_004151446.1 VirK/YbjX family protein -
LCH45_RS09950 2041700..2042353 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LCH45_RS09955 2042350..2042541 - 192 WP_002911395.1 YebW family protein -
LCH45_RS09960 2042639..2042878 - 240 WP_002911393.1 YebV family protein -
LCH45_RS09965 2042994..2044427 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T217810 NZ_CP083932:2039849-2039951 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT217810 NZ_CP083932:c2039958-2039813 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References