Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1758839..1758984 Replicon chromosome
Accession NZ_CP083768
Organism Klebsiella pneumoniae strain KSB1_9E isolate KSB1_9E

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1758875..1758977 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1758839..1758984 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LB480_RS08520 1753969..1756029 + 2061 WP_060415693.1 oligopeptidase B -
LB480_RS08525 1756033..1756692 - 660 WP_002911407.1 exodeoxyribonuclease X -
LB480_RS08530 1756771..1757001 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LB480_RS08535 1757114..1757488 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LB480_RS08540 1757492..1758361 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
LB480_RS08545 1758378..1758716 + 339 WP_048982383.1 YebY family protein -
- 1758839..1758984 - 146 - - Antitoxin
- 1758875..1758977 + 103 - - Toxin
LB480_RS08550 1759353..1759496 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LB480_RS08555 1759601..1760569 - 969 WP_004151446.1 VirK/YbjX family protein -
LB480_RS08560 1760726..1761379 + 654 WP_060415692.1 protein-serine/threonine phosphatase -
LB480_RS08565 1761376..1761567 - 192 WP_002911395.1 YebW family protein -
LB480_RS08570 1761665..1761904 - 240 WP_002911393.1 YebV family protein -
LB480_RS08575 1762020..1763453 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T217272 NZ_CP083768:1758875-1758977 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT217272 NZ_CP083768:c1758984-1758839 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References