Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1023888..1024489 Replicon chromosome
Accession NZ_CP083721
Organism Bradyrhizobium sp. 41S5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HAP47_RS04840 Protein ID WP_173639207.1
Coordinates 1023888..1024184 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HAP47_RS04845 Protein ID WP_173639206.1
Coordinates 1024181..1024489 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAP47_RS04825 (HAP47_0004840) 1019469..1021157 + 1689 WP_173639209.1 2,3-epoxybenzoyl-CoA dihydrolase -
HAP47_RS04830 (HAP47_0004845) 1021327..1022763 + 1437 WP_173640655.1 benzoyl-CoA 2,3-epoxidase subunit BoxB -
HAP47_RS04835 (HAP47_0004850) 1023002..1023841 + 840 WP_173639208.1 alpha/beta hydrolase -
HAP47_RS04840 (HAP47_0004855) 1023888..1024184 - 297 WP_173639207.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HAP47_RS04845 (HAP47_0004860) 1024181..1024489 - 309 WP_173639206.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HAP47_RS04850 (HAP47_0004865) 1024732..1025532 - 801 WP_173639205.1 SDR family oxidoreductase -
HAP47_RS04855 (HAP47_0004870) 1025785..1026015 - 231 WP_173639204.1 hypothetical protein -
HAP47_RS04860 (HAP47_0004875) 1026215..1026928 + 714 WP_173639203.1 sulfite exporter TauE/SafE family protein -
HAP47_RS04865 (HAP47_0004880) 1026941..1027999 - 1059 WP_173639202.1 polysaccharide deacetylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11060.47 Da        Isoelectric Point: 4.6556

>T217158 WP_173639207.1 NZ_CP083721:c1024184-1023888 [Bradyrhizobium sp. 41S5]
VKLVWTRFALSDRDDIFSYIEAENPRAAVHVDEQIADAARRLLDFPDSGRPGRVAGTRELVIPRTPYVAAYLVDGETVRI
LRVLHGAQMWPDELANDD

Download         Length: 297 bp

>T217158 NZ_CP113925:2457473-2457754 [Bifidobacterium sp. ESL0728]
ATGCTTGATTCGGTTTTCCGTACATCGCAATTCAAGCGCGATTTCAAGGCTCTCGTACGAAAACATTACAATCCAGAGAC
GATGAGAGCCGCGGTGAGTGCGCTAATGGGCCAGAATAAAGACCTGCTTCGCACCAAATACCGCGATCATCCACTCACTG
GAGAGTGGAAAGGCTACCGCGAAATCCACCTTGAAGGCGATTGGCTGGTCATCTACCGTATCAAGAAAACCGAGTTGCAA
CTCGTTCTGACCAGAACCGGTTCCCATGACGATCTCTTTTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11311.77 Da        Isoelectric Point: 8.6579

>AT217158 WP_173639206.1 NZ_CP083721:c1024489-1024181 [Bradyrhizobium sp. 41S5]
MASNALVQTRIDADVKEKATAVLENMGLTVSDAVRILLTRTANEGTLPLELVSNSQAYDSWFREKVRQALADTRPSLDDS
EVDAHFAQRRAAALRKAAERKR

Download         Length: 309 bp

>AT217158 NZ_CP113925:2457223-2457480 [Bifidobacterium sp. ESL0728]
ATGACTACGACGACCATCAGCTTCAGAACCGACAAAACCATCAAGGAGCAGGCCAAGCAGTTATACGCCGAGATGGGCAT
GGATCTCTCAACGGCTATCAATATTTTCCTGCGACAGTCAATCACCGACAACGCCATGCCATTTCGAGTCACACGCGACA
AGCCTGAAAACATCGCCGCTCGCGGTCAGGCCGAACATCACGAAGGGAAAACCTTCCAATCAGTAGACGACCTGATGGAG
GATTTGAACCATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References