Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 744785..745056 Replicon chromosome
Accession NZ_CP083701
Organism Escherichia coli strain SUISSEKPC3NDM5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 744915..745018 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 744785..745056 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9O95_RS03755 741340..742002 - 663 WP_000944256.1 exodeoxyribonuclease X -
K9O95_RS03760 742026..742682 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
K9O95_RS03765 742784..743014 - 231 WP_000916763.1 DNA polymerase III subunit theta -
K9O95_RS03770 743153..743527 + 375 WP_000168747.1 CopC domain-containing protein YobA -
K9O95_RS03775 743531..744403 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
K9O95_RS03780 744416..744757 + 342 WP_000976472.1 YebY family protein -
- 744785..745056 - 272 - - Antitoxin
- 744915..745018 + 104 - - Toxin
K9O95_RS03785 745153..745809 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
K9O95_RS03790 745810..746001 - 192 WP_001296140.1 YebW family protein -
K9O95_RS03795 746106..746342 - 237 WP_001295499.1 YebV family protein -
K9O95_RS03800 746460..747899 - 1440 WP_061344305.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 673426..761671 88245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T217095 NZ_CP083701:744915-745018 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT217095 NZ_CP083701:c745056-744785 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References