Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1977203..1977349 Replicon chromosome
Accession NZ_CP082898
Organism Klebsiella aerogenes strain KAE3SP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1977238..1977341 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1977203..1977349 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6006_RS09245 (K6006_09245) 1972312..1974372 + 2061 WP_032708611.1 oligopeptidase B -
K6006_RS09250 (K6006_09250) 1974375..1975034 - 660 WP_015366006.1 exodeoxyribonuclease X -
K6006_RS09255 (K6006_09255) 1975114..1975344 - 231 WP_015366007.1 DNA polymerase III subunit theta -
K6006_RS09260 (K6006_09260) 1975479..1975853 + 375 WP_015366008.1 CopC domain-containing protein YobA -
K6006_RS09265 (K6006_09265) 1975857..1976726 + 870 WP_032708610.1 copper homeostasis membrane protein CopD -
K6006_RS09270 (K6006_09270) 1976740..1977081 + 342 WP_015705946.1 YebY family protein -
- 1977203..1977349 - 147 - - Antitoxin
- 1977238..1977341 + 104 - - Toxin
K6006_RS09275 (K6006_09275) 1977469..1978416 - 948 WP_032709999.1 spore coat U domain-containing protein -
K6006_RS09280 (K6006_09280) 1978435..1980759 - 2325 WP_032708542.1 fimbria/pilus outer membrane usher protein -
K6006_RS09285 (K6006_09285) 1980762..1981511 - 750 WP_015366013.1 molecular chaperone -
K6006_RS09290 (K6006_09290) 1981529..1982047 - 519 WP_015366014.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T215505 NZ_CP082898:1977238-1977341 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 147 bp

>AT215505 NZ_CP082898:c1977349-1977203 [Klebsiella aerogenes]
TAATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References