Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 2358273..2358807 Replicon chromosome
Accession NC_007907
Organism Desulfitobacterium hafniense Y51

Toxin (Protein)


Gene name relE Uniprot ID Q24VX0
Locus tag DSY_RS10840 Protein ID WP_005812628.1
Coordinates 2358535..2358807 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G9XNU5
Locus tag DSY_RS10835 Protein ID WP_005812625.1
Coordinates 2358273..2358542 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSY_RS10800 2353502..2353744 - 243 WP_005812608.1 type II toxin-antitoxin system YafQ family toxin -
DSY_RS10805 2353780..2354358 - 579 WP_005812610.1 Uma2 family endonuclease -
DSY_RS10810 2354543..2354848 - 306 WP_005812612.1 type II toxin-antitoxin system RelE/ParE family toxin -
DSY_RS10815 2354838..2355104 - 267 WP_005812614.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
DSY_RS10820 2355432..2356952 - 1521 WP_041272845.1 hypothetical protein -
DSY_RS10825 2357072..2357721 - 650 Protein_2129 hypothetical protein -
DSY_RS10830 2357775..2357972 - 198 WP_005812623.1 hypothetical protein -
DSY_RS10835 2358273..2358542 + 270 WP_005812625.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DSY_RS10840 2358535..2358807 + 273 WP_005812628.1 type II toxin-antitoxin system YafQ family toxin Toxin
DSY_RS10845 2358975..2360576 - 1602 WP_011460008.1 glucose-6-phosphate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-87)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10574.38 Da        Isoelectric Point: 9.7122

>T21502 WP_005812628.1 NC_007907:2358535-2358807 [Desulfitobacterium hafniense Y51]
MLRVRYSSRFKKDFKILVKRGYNVGLFEDVLNLLVQEKALPQKYLDHPLAGNYAGHRECHITPDWLLIYKIEKDILILSL
TRTGTHSDLF

Download         Length: 273 bp

>T21502 NC_007907:2358535-2358807 [Desulfitobacterium hafniense Y51]
ATGCTTAGAGTCAGGTACTCCAGCCGATTCAAAAAAGACTTTAAAATTCTCGTTAAGCGCGGCTATAATGTCGGGCTGTT
TGAAGATGTCCTTAACCTTCTTGTTCAAGAGAAGGCGCTTCCTCAAAAATATCTCGACCATCCTCTTGCCGGTAACTATG
CTGGGCATCGGGAGTGCCATATCACTCCTGACTGGCTGCTAATTTATAAAATTGAAAAGGACATCTTGATATTGTCTTTG
ACACGAACAGGAACACATAGTGATCTGTTTTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9882.22 Da        Isoelectric Point: 4.2412

>AT21502 WP_005812625.1 NC_007907:2358273-2358542 [Desulfitobacterium hafniense Y51]
VANTTNLNIRVDEELKCKAEAIFAELGLNMSTAMNIFLRCSVRYGGIPFDLRIEQPNAETLAVIDDVNNNRNMSKTFDSV
SALMEDLNA

Download         Length: 270 bp

>AT21502 NC_007907:2358273-2358542 [Desulfitobacterium hafniense Y51]
GTGGCTAATACTACTAACCTAAATATTCGTGTGGATGAGGAGTTAAAATGCAAGGCTGAGGCCATATTTGCGGAGCTAGG
GCTTAATATGTCCACAGCTATGAATATTTTCCTGCGTTGCTCCGTTCGCTACGGCGGCATTCCTTTCGACCTTCGCATTG
AACAGCCTAATGCAGAAACCTTGGCTGTTATCGATGATGTCAATAACAATCGCAATATGAGCAAAACCTTTGACAGCGTC
AGTGCTTTAATGGAGGATCTGAATGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q24VX0

Antitoxin

Source ID Structure
AlphaFold DB A0A098B195

References