Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2267332..2267500 Replicon chromosome
Accession NZ_CP082360
Organism Klebsiella sp. CTHL.F3a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2267390..2267493 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2267332..2267500 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7H21_RS10665 (K7H21_10665) 2262459..2264519 + 2061 WP_223035765.1 oligopeptidase B -
K7H21_RS10670 (K7H21_10670) 2264526..2265185 - 660 WP_004122030.1 exodeoxyribonuclease X -
K7H21_RS10675 (K7H21_10675) 2265264..2265494 - 231 WP_004122029.1 DNA polymerase III subunit theta -
K7H21_RS10680 (K7H21_10680) 2265630..2266004 + 375 WP_004122028.1 CopC domain-containing protein YobA -
K7H21_RS10685 (K7H21_10685) 2266009..2266878 + 870 WP_087828997.1 copper homeostasis membrane protein CopD -
K7H21_RS10690 (K7H21_10690) 2266895..2267233 + 339 WP_223035766.1 YebY family protein -
- 2267332..2267500 - 169 - - Antitoxin
- 2267390..2267493 + 104 - - Toxin
K7H21_RS10695 (K7H21_10695) 2267618..2268577 - 960 WP_049114593.1 spore coat protein U domain-containing protein -
K7H21_RS10700 (K7H21_10700) 2268592..2270922 - 2331 WP_223035767.1 fimbria/pilus outer membrane usher protein -
K7H21_RS10705 (K7H21_10705) 2270925..2271689 - 765 WP_123829169.1 molecular chaperone -
K7H21_RS10710 (K7H21_10710) 2271708..2272226 - 519 WP_004122022.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T214727 NZ_CP082360:2267390-2267493 [Klebsiella sp. CTHL.F3a]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT214727 NZ_CP082360:c2267500-2267332 [Klebsiella sp. CTHL.F3a]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References