Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2023369..2023637 Replicon chromosome
Accession NZ_CP082357
Organism Escherichia coli strain VCSW7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2023496..2023599 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2023369..2023637 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7X31_RS09435 2019922..2020584 - 663 WP_000944256.1 exodeoxyribonuclease X -
K7X31_RS09440 2020608..2021264 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
K7X31_RS09445 2021366..2021596 - 231 WP_000916763.1 DNA polymerase III subunit theta -
K7X31_RS09450 2021735..2022109 + 375 WP_223025071.1 CopC domain-containing protein YobA -
K7X31_RS09455 2022113..2022985 + 873 WP_054495243.1 copper homeostasis membrane protein CopD -
K7X31_RS09460 2022998..2023339 + 342 WP_000976472.1 YebY family protein -
- 2023369..2023637 - 269 - - Antitoxin
- 2023496..2023599 + 104 - - Toxin
K7X31_RS09465 2023734..2024390 + 657 WP_223025072.1 protein-serine/threonine phosphatase -
K7X31_RS09470 2024391..2024582 - 192 WP_001296140.1 YebW family protein -
K7X31_RS09475 2024687..2024923 - 237 WP_001295499.1 YebV family protein -
K7X31_RS09480 2025041..2026480 - 1440 WP_223025073.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T214699 NZ_CP082357:2023496-2023599 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT214699 NZ_CP082357:c2023637-2023369 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References