Detailed information of TA system TA021294

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-PumB/upstrm_HI1419-dnstrm_HI1420
• Location: 2644051..2644692
• Replicon: chromosome
• Accession: NC_007511
• Organism: Burkholderia lata

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BCEP18194_RS34295
• Protein ID: WP_011355906.1
• Coordinates: 2644051..2644389 (+)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: PumB
• Uniprot ID: -
• Locus tag: BCEP18194_RS34300
• Protein ID: WP_011355907.1
• Coordinates: 2644393..2644692 (+)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (16-109)

Antitoxin

• Uncharacterized protein HI1420 (6-93)

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 12697.57 Da
• Isoelectric Point: 9.5686

>T21294 WP_011355906.1 NC_007511:2644051-2644389 [Burkholderia lata]
MVDTLQSMPYSAPTFSIRTTDVFDAWFSRLPDRVAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRG
TIWVILLCGGDKSTQQADIRAAHAMLAHLDME

Nucleotide

• Length: 339 bp

>T21294 NC_007511:2644051-2644389 [Burkholderia lata]
ATGGTTGACACACTGCAATCCATGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGACGTCTTCGACGCCTGGTT
TTCCCGCCTGCCGGATCGCGTCGCGAAGCGCCGCATCCAGGCGCGCATCGACCGCCTCTCGATGGGCAATCCGGGCGACT
GGAAGTCCGCCGGCTCGCCGGTCGTCGAGATGCGGATCGACCACGGCCCCGGATATCGCGTCTACTACGTGAGGCGCGGA
ACGATCTGGGTCATCCTGCTCTGCGGCGGCGATAAATCGACACAGCAGGCCGACATCCGCGCCGCGCACGCGATGCTCGC
GCATCTCGACATGGAGTAA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 10615.94 Da
• Isoelectric Point: 6.2081

>AT21294 WP_011355907.1 NC_007511:2644393-2644692 [Burkholderia lata]
MDKISTRPWDSADHLKTEDDMADYFEACLQEGGDDPAFIAHALGVIARAHGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGSKAHA

Nucleotide

• Length: 300 bp

>AT21294 NC_007511:2644393-2644692 [Burkholderia lata]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGATCACCTGAAAACCGAAGACGACATGGCCGACTACTTCGAAGC
GTGCCTGCAGGAAGGCGGCGACGATCCGGCCTTCATCGCGCACGCGCTCGGCGTGATCGCGCGTGCACACGGCATGTCGC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAACCCGAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCATGA