Detailed information of TA system TA021287

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 1808495..1809171
• Replicon: chromosome
• Accession: NC_007510
• Organism: Burkholderia lata

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: BCEP18194_RS14090
• Protein ID: WP_011351948.1
• Coordinates: 1808755..1809171 (+)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: Q39GM8
• Locus tag: BCEP18194_RS14085
• Protein ID: WP_011351947.1
• Coordinates: 1808495..1808758 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-130)

Antitoxin

• SpoVT-AbrB domain (7-55)

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 14617.78 Da
• Isoelectric Point: 7.9142

>T21287 WP_011351948.1 NC_007510:1808755-1809171 [Burkholderia lata]
VTTLYMLDTNICSFIMRERPPVVLSRLQSCVNAQHRIVVSAITYAEMRFGAVGRKASPKHAELVTAFVSRLDGVLSWDTA
AVDATAAIRADLAARGTPIGANDASIAGHAIAAGAVLVTHNSREFGRVAGLSLEDWAV

Nucleotide

• Length: 417 bp

>T21287 NC_007510:1808755-1809171 [Burkholderia lata]
GTGACCACGCTCTACATGCTCGACACGAACATCTGTTCGTTCATCATGCGCGAGCGGCCGCCCGTGGTGCTGTCGCGGTT
GCAATCGTGCGTCAATGCGCAGCACCGGATCGTCGTCTCCGCAATTACGTATGCCGAAATGCGATTTGGCGCGGTCGGCA
GGAAGGCTTCACCGAAGCATGCGGAACTCGTGACGGCTTTTGTGTCGCGGCTGGATGGCGTGCTGTCGTGGGATACGGCG
GCCGTCGATGCAACGGCCGCGATTCGTGCCGATCTCGCCGCGCGCGGCACGCCGATCGGCGCGAACGACGCGTCGATCGC
CGGGCATGCGATCGCGGCCGGTGCGGTGCTCGTCACCCACAACAGCCGCGAGTTCGGCCGTGTCGCCGGATTGTCGCTCG
AAGACTGGGCGGTCTGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9689.86 Da
• Isoelectric Point: 4.3654

>AT21287 WP_011351947.1 NC_007510:1808495-1808758 [Burkholderia lata]
MRTVSIFKNARNQAIRIPKDMEFEGVTELEIRREGDTLLLRPVRPTWLSFASEPPADADFLAERPAVIESGRFDLSDDGA
APTGSDQ

Nucleotide

• Length: 264 bp

>AT21287 NC_007510:1808495-1808758 [Burkholderia lata]
ATGCGCACCGTTTCCATTTTCAAGAACGCTCGTAACCAGGCAATCCGCATCCCGAAGGACATGGAGTTCGAGGGGGTGAC
GGAACTCGAGATCCGCCGCGAGGGCGACACGCTGCTGCTGCGGCCCGTGCGGCCCACGTGGCTCTCGTTCGCGAGCGAAC
CGCCGGCCGACGCCGACTTCCTCGCCGAACGCCCGGCCGTCATCGAGTCCGGCCGCTTCGACCTGTCCGACGATGGCGCC
GCACCGACGGGGTCCGACCAGTGA

Structures

Antitoxin

• AlphaFold DB: Q39GM8