Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 88891..89413 Replicon chromosome
Accession NC_007484
Organism Nitrosococcus oceani ATCC 19707

Toxin (Protein)


Gene name - Uniprot ID Q3JEX7
Locus tag NOC_RS00630 Protein ID WP_011330226.1
Coordinates 88891..89154 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID Q3JEX6
Locus tag NOC_RS00635 Protein ID WP_002812971.1
Coordinates 89144..89413 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOC_RS00610 85072..85677 - 606 WP_002812620.1 DNA-3-methyladenine glycosylase -
NOC_RS16535 85910..86341 - 432 WP_147094527.1 tyrosine-type recombinase/integrase -
NOC_RS00620 86785..87738 + 954 WP_147094525.1 hypothetical protein -
NOC_RS00625 87829..88731 + 903 WP_002814242.1 sulfotransferase domain-containing protein -
NOC_RS00630 88891..89154 + 264 WP_011330226.1 BrnT family toxin Toxin
NOC_RS00635 89144..89413 + 270 WP_002812971.1 hypothetical protein Antitoxin
NOC_RS00640 89478..89768 + 291 WP_036497825.1 BrnT family toxin -
NOC_RS00645 89746..89982 + 237 WP_002813145.1 BrnA antitoxin family protein -
NOC_RS00650 90148..90867 + 720 WP_011330228.1 SIMPL domain-containing protein -
NOC_RS00655 91778..92896 + 1119 WP_002812613.1 nitrite reductase, copper-containing -
NOC_RS16540 93439..93741 + 303 Protein_93 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 87829..90867 3038


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10095.59 Da        Isoelectric Point: 7.1356

>T21264 WP_011330226.1 NC_007484:88891-89154 [Nitrosococcus oceani ATCC 19707]
MDEFEFDEAKSQANLDKHGINFVAAQGLWKDPCLLEIRAKSEGEPRFLLIGKIGEKHWSAVVTYREACIRLISVRRSRKK
EIELYES

Download         Length: 264 bp

>T21264 NC_007484:88891-89154 [Nitrosococcus oceani ATCC 19707]
ATGGATGAGTTTGAATTCGACGAAGCCAAAAGTCAGGCCAATCTGGATAAGCACGGTATTAATTTCGTGGCCGCCCAAGG
TCTGTGGAAAGACCCATGCCTGCTGGAAATACGAGCAAAATCAGAGGGTGAGCCGAGGTTTCTGCTGATAGGCAAGATTG
GCGAAAAGCACTGGTCGGCTGTCGTCACATACAGGGAAGCTTGTATTCGTTTGATTTCAGTCAGGCGCTCTCGCAAGAAG
GAGATTGAACTCTATGAAAGCTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10038.25 Da        Isoelectric Point: 4.8723

>AT21264 WP_002812971.1 NC_007484:89144-89413 [Nitrosococcus oceani ATCC 19707]
MKAKDFDKKFDEGQEDIIDDLDLSTARRTNLEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANKPL
NGDASGGAH

Download         Length: 270 bp

>AT21264 NC_007484:89144-89413 [Nitrosococcus oceani ATCC 19707]
ATGAAAGCTAAAGACTTTGATAAAAAATTCGACGAAGGCCAGGAAGATATTATTGACGACCTTGATCTGTCCACAGCCCG
TCGCACCAACCTGGAACAAAAGCGAATCAACGTGGACTTTCCTGCCTGGGTCGTAGAGTCGTTGGATCGAGAGGCCGCGC
GTATTGGCGTTACCCGCCAATCAATCATCAAGGTGTGGCTGGTTGAGCGCCTTCAAGCAGAATCTGCTAACAAGCCGCTC
AATGGTGACGCCTCAGGCGGCGCACATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E2ZAR8

Antitoxin

Source ID Structure
AlphaFold DB A0A0E2Z6A0

References