Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 308511..309061 Replicon chromosome
Accession NZ_CP080635
Organism Shewanella putrefaciens strain YZ-J

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K3G22_RS01465 Protein ID WP_025008030.1
Coordinates 308511..308810 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K3G22_RS01470 Protein ID WP_025008031.1
Coordinates 308819..309061 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3G22_RS01440 (K3G22_01440) 303779..304345 - 567 WP_025008028.1 XRE family transcriptional regulator -
K3G22_RS01445 (K3G22_01445) 304509..305696 + 1188 WP_011787676.1 benzoate/H(+) symporter BenE family transporter -
K3G22_RS01450 (K3G22_01450) 305748..306224 - 477 WP_011787677.1 GNAT family N-acetyltransferase -
K3G22_RS01455 (K3G22_01455) 306956..307159 + 204 WP_061782969.1 hypothetical protein -
K3G22_RS01460 (K3G22_01460) 307393..308259 + 867 WP_025008029.1 DUF6236 family protein -
K3G22_RS01465 (K3G22_01465) 308511..308810 - 300 WP_025008030.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K3G22_RS01470 (K3G22_01470) 308819..309061 - 243 WP_025008031.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K3G22_RS01475 (K3G22_01475) 309539..310282 - 744 WP_025008032.1 hypothetical protein -
K3G22_RS01480 (K3G22_01480) 310314..311573 - 1260 WP_025008033.1 beta-ketoacyl-ACP synthase -
K3G22_RS01485 (K3G22_01485) 311574..312299 - 726 WP_011918514.1 3-ketoacyl-ACP reductase FabG2 -
K3G22_RS01490 (K3G22_01490) 312412..312945 - 534 WP_128090195.1 hotdog family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-66)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11571.40 Da        Isoelectric Point: 9.5972

>T212321 WP_025008030.1 NZ_CP080635:c308810-308511 [Shewanella putrefaciens]
MKNKRYKLSKLAQTHLLKIKDYTIQHFSESQWHKYKESLISGLQMLADNPGLGRSCEDIYPNGFYFPIAKHTAYFTKEDD
FILIVAMLGQPQLPQNHLK

Download         Length: 300 bp

>T212321 NZ_CP107002:3561455-3561673 [Escherichia coli]
ATGTCCGAAAAATTTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8936.14 Da        Isoelectric Point: 5.0621

>AT212321 WP_025008031.1 NZ_CP080635:c309061-308819 [Shewanella putrefaciens]
VQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNIVDGEDFLNAL

Download         Length: 243 bp

>AT212321 NZ_CP107002:3561055-3561429 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References