211877

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1178474..1179149 Replicon chromosome
Accession NZ_CP080422
Organism Shewanella alkalitolerans strain FJAT-54031

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K0J45_RS05225 Protein ID WP_220044545.1
Coordinates 1178694..1179149 (+) Length 152 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K0J45_RS05220 Protein ID WP_220045222.1
Coordinates 1178474..1178713 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0J45_RS05195 (K0J45_05195) 1173845..1174639 + 795 WP_220044540.1 sulfite exporter TauE/SafE family protein -
K0J45_RS05200 (K0J45_05200) 1174755..1175606 + 852 WP_220044541.1 thymidylate synthase -
K0J45_RS05205 (K0J45_05205) 1175913..1177088 + 1176 WP_220044542.1 Na+/H+ antiporter NhaA -
K0J45_RS05210 (K0J45_05210) 1177085..1177468 + 384 WP_220044543.1 hypothetical protein -
K0J45_RS05215 (K0J45_05215) 1177489..1178397 + 909 WP_220044544.1 transcriptional activator NhaR -
K0J45_RS05220 (K0J45_05220) 1178474..1178713 + 240 WP_220045222.1 succinate dehydrogenase assembly factor 2 Antitoxin
K0J45_RS05225 (K0J45_05225) 1178694..1179149 + 456 WP_220044545.1 hypothetical protein Toxin
K0J45_RS05230 (K0J45_05230) 1179161..1180774 - 1614 WP_011864851.1 L-aspartate oxidase -
K0J45_RS05235 (K0J45_05235) 1180974..1181552 + 579 WP_011864852.1 RNA polymerase sigma factor RpoE -
K0J45_RS05240 (K0J45_05240) 1181592..1182194 + 603 WP_220044546.1 RseA family anti-sigma factor -
K0J45_RS05245 (K0J45_05245) 1182260..1183192 + 933 WP_011864854.1 MucB/RseB C-terminal domain-containing protein -
K0J45_RS05250 (K0J45_05250) 1183200..1183676 + 477 WP_220044547.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-149)

Antitoxin

Flavinator of succinate dehydrogenase

(4-74)


Sequences

Toxin        


Download         Length: 152 a.a.        Molecular weight: 17898.85 Da        Isoelectric Point: 8.2867

>T211877 WP_220044545.1 NZ_CP080422:1178694-1179149 [Shewanella alkalitolerans]
VAGRRHNFHLTASFDQRLSLVCFAALCLSAFLVWPPIASLWFLTLKYGLLTATITFFLYQFIALRRWSLAFWLDESGRIG
LLRDELDSHTQVQQVDEASEQHLSYRRIWVSPLVVLFWLYEGEQKRLVILWRDMFDDTGYRHLCRLLLRFG

Download         Length: 456 bp

>T211877 NZ_CP106816:1179-1457 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9168.72 Da        Isoelectric Point: 4.5679

>AT211877 WP_220045222.1 NZ_CP080422:1178474-1178713 [Shewanella alkalitolerans]
MNIARVRWACRRGMLELDVLFQPFVETQYEQLSIDDKAVFVRLLECEDPELFAWFMGHEACPDPLLAEMVVKVRGRAAP

Download         Length: 240 bp

>AT211877 NZ_CP106816:994-1179 [Neisseria gonorrhoeae]
ATGCAAACCACTATCCCCACCGGTTCAATCCGCACCTTTGGCGATTACGGCGTGATGTACATCGTCGGCACGCCTGCCGA
ACAGCTTCCGGACGGCGATTGGCTCGTAAATATTGAACTGCCGGAAAGCGGCGAACACACGCAATACAAACTGTCCCACA
TCGTTCAAGACCCAAAGGCTGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References