Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3422242..3422917 Replicon chromosome
Accession NZ_CP080417
Organism Shewanella halotolerans strain FJAT-53555

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag K0H81_RS14885 Protein ID WP_220058827.1
Coordinates 3422242..3422697 (-) Length 152 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag K0H81_RS14890 Protein ID WP_041406484.1
Coordinates 3422678..3422917 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H81_RS14860 (K0H81_14860) 3417715..3418191 - 477 WP_220058825.1 SoxR reducing system RseC family protein -
K0H81_RS14865 (K0H81_14865) 3418199..3419131 - 933 WP_220058826.1 MucB/RseB C-terminal domain-containing protein -
K0H81_RS14870 (K0H81_14870) 3419197..3419799 - 603 WP_011864853.1 RseA family anti-sigma factor -
K0H81_RS14875 (K0H81_14875) 3419839..3420417 - 579 WP_011864852.1 RNA polymerase sigma factor RpoE -
K0H81_RS14880 (K0H81_14880) 3420617..3422230 + 1614 WP_011864851.1 L-aspartate oxidase -
K0H81_RS14885 (K0H81_14885) 3422242..3422697 - 456 WP_220058827.1 hypothetical protein Toxin
K0H81_RS14890 (K0H81_14890) 3422678..3422917 - 240 WP_041406484.1 succinate dehydrogenase assembly factor 2 Antitoxin
K0H81_RS14895 (K0H81_14895) 3422994..3423902 - 909 WP_011864848.1 transcriptional activator NhaR -
K0H81_RS14900 (K0H81_14900) 3423923..3424306 - 384 WP_220058828.1 hypothetical protein -
K0H81_RS14905 (K0H81_14905) 3424303..3425478 - 1176 WP_220058829.1 Na+/H+ antiporter NhaA -
K0H81_RS14910 (K0H81_14910) 3425785..3426636 - 852 WP_144201092.1 thymidylate synthase -
K0H81_RS14915 (K0H81_14915) 3426752..3427546 - 795 WP_144201090.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-149)

Antitoxin

Flavinator of succinate dehydrogenase

(4-75)


Sequences

Toxin        


Download         Length: 152 a.a.        Molecular weight: 17958.94 Da        Isoelectric Point: 7.8235

>T211870 WP_220058827.1 NZ_CP080417:c3422697-3422242 [Shewanella halotolerans]
VAGRRHNFHLTVSFDQRLSLVCFAALCLSAFLVWPPIASLWFLTLKYGLLTATITFFLYQFIALRRWSLAFWLDESGRIG
FIHDELDSHTQVQQVDEAIEQQLSYRRIWVSPLVVLFWLYEGEQKRLVILWRDMFDDTGYRHLCRLLLRFG

Download         Length: 456 bp

>T211870 NZ_CP106811:c1659310-1659128 [Neisseria gonorrhoeae]
TTGAATAGCCTAGACGTTATTGCCCTACTCAAACAAGACGGTTGGTATAAAGTTGCACAATCCGGGAGCCATTCGCAATA
TAAGCACCCAACAAAAAAAGGCCGTGTAACCGTGCCGCACCCGAAAAAAGACTTGCCGACAGGTACTGTAAAAAATATCT
ATAAGCAAGCCGGTTTGAAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9169.66 Da        Isoelectric Point: 4.5535

>AT211870 WP_041406484.1 NZ_CP080417:c3422917-3422678 [Shewanella halotolerans]
MNIARVRWACRRGMLELDVLFQPFVETQYEQLSIDDKAVFVRLLECEDPELFAWFMGHEACPDPQLADMVVKVRGRAAP

Download         Length: 240 bp

>AT211870 NZ_CP106811:c1659026-1658625 [Neisseria gonorrhoeae]
ATGTTTATCCCTGCCGCCCTGCACAAAGACGAACATTCGGCATATGGCGTAACCATCCCCGACCTTCCCGGCTGTTTCTC
TTGCGGCGACACCGTTGAAGAAGCCGTCGCCAACGCCCGTTCTGCCGCCTATATGCATATTGACGGTATGATTGAGGACG
GAGGGTTCAAAAACCTTGCCGTAAGCAGCATTGCCGATTTGAGCCAAGAACCTGATTATCATGGGGCAACATGGGTAATG
ATTGAAATCGACCCTGCAAAAATCAGTCGGCAGCAAATCCGATTCAACGTCAGCTGGCCGCAATACCTTCTTGATAGAGT
GGATGAATATACATCCGCAAATCATGAAACCCGTAGCGGTTTTTTAGCCAAAGCCGCCCTGCTCACCATGAATCAGGCAT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References