Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3654685..3655776 Replicon chromosome
Accession NZ_CP080414
Organism Shewanella zhangzhouensis strain FJAT-52072

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag K0H63_RS16080 Protein ID WP_220065551.1
Coordinates 3654685..3655413 (-) Length 243 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag K0H63_RS16085 Protein ID WP_220065552.1
Coordinates 3655414..3655776 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0H63_RS16055 (K0H63_16055) 3651273..3651692 + 420 WP_220065547.1 CBS domain-containing protein -
K0H63_RS16060 (K0H63_16060) 3651741..3652430 - 690 WP_203324853.1 LrgB family protein -
K0H63_RS16065 (K0H63_16065) 3652430..3652861 - 432 WP_220065548.1 CidA/LrgA family protein -
K0H63_RS16070 (K0H63_16070) 3652965..3653873 + 909 WP_220065549.1 LysR family transcriptional regulator -
K0H63_RS16075 (K0H63_16075) 3653850..3654665 - 816 WP_220065550.1 hypothetical protein -
K0H63_RS16080 (K0H63_16080) 3654685..3655413 - 729 WP_220065551.1 RES family NAD+ phosphorylase Toxin
K0H63_RS16085 (K0H63_16085) 3655414..3655776 - 363 WP_220065552.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
K0H63_RS16090 (K0H63_16090) 3656019..3656672 + 654 WP_220065553.1 oxygen-insensitive NAD(P)H nitroreductase -
K0H63_RS16095 (K0H63_16095) 3656812..3657462 + 651 WP_220065554.1 DNA-J related domain-containing protein -
K0H63_RS16100 (K0H63_16100) 3657622..3658368 + 747 WP_220065555.1 thiol:disulfide interchange protein DsbA/DsbL -
K0H63_RS16105 (K0H63_16105) 3658811..3660148 + 1338 WP_220065556.1 Na+/H+ antiporter NhaC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(50-198)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(69-118)


Sequences

Toxin        


Download         Length: 243 a.a.        Molecular weight: 27733.58 Da        Isoelectric Point: 5.6422

>T211867 WP_220065551.1 NZ_CP080414:c3655413-3654685 [Shewanella zhangzhouensis]
MDLLSIPEVPYEGSCYRLVESQEEAATLSLVDNFDEQMLLESLLDGAKPPYREGTAHLHYLLKTPFRYPPLRHGSRFGTR
LMPSFFYGSESVQTCLTEVAYYRFVFLQDMAVPYQGVLHSEHMMFRVLLSAKRCADLTRIADDTLQRQLTHGEDYRFTQA
LGQQLLERDCQLIRSYSAREPGGVNLAVADPGVMASAPLDQSYWICQLEPARLAFTERGRGNMPRYYEVEAFFREGRLPR
PA

Download         Length: 729 bp

>T211867 NZ_CP106809:c1642866-1642684 [Neisseria gonorrhoeae]
TTGAATAGCCTAGACGTTATTGCCCTACTCAAACAAGACGGTTGGTATAAAGTTGCACAATCCGGGAGCCATTCGCAATA
TAAGCACCCAACAAAAAAAGGCCGTGTAACCGTGCCGCACCCGAAAAAAGACTTGCCGACAGGTACTGTAAAAAATATCT
ATAAGCAAGCCGGTTTGAAGTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 12950.90 Da        Isoelectric Point: 10.2283

>AT211867 WP_220065552.1 NZ_CP080414:c3655776-3655414 [Shewanella zhangzhouensis]
MSAIAKPTASGVLFKAFTNACQALELTNAEASHIIGVNPSTLSRNAANGFKPESKQGELQLQLVRLYRSLYALAGGQQDF
MRHWLNSPNHALGGIPRELVKSVVGLVSVNQYLDAMRGKV

Download         Length: 363 bp

>AT211867 NZ_CP106809:c1642582-1642181 [Neisseria gonorrhoeae]
ATGTTTATCCCTGCCGCCCTGCACAAAGACGAACATTCGGCATATGGCGTAACCATCCCCGACCTTCCCGGCTGTTTCTC
TTGCGGCGACACCGTTGAAGAAGCCGTCGCCAACGCCCGTTCTGCCGCCTATATGCATATTGACGGTATGATTGAGGACG
GAGGGTTCAAAAACCTTGCCGTAAGCAGCATTGCCGATTTGAGCCAAGAACCTGATTATCATGGGGCAACATGGGTAATG
ATTGAAATCGACCCTGCAAAAATCAGTCGGCAGCAAATCCGATTCAACGTCAGCTGGCCGCAATACCTTCTTGATAGAGT
GGATGAATATACATCCGCAAATCATGAAACCCGTAGCGGTTTTTTAGCCAAAGCCGCCCTGCTCACCATGAATCAGGCAT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References