Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2007128..2007273 Replicon chromosome
Accession NZ_CP080297
Organism Klebsiella pneumoniae strain KP-C76

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2007164..2007266 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2007128..2007273 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0E64_RS09825 (K0E64_09825) 2002258..2004318 + 2061 WP_004151449.1 oligopeptidase B -
K0E64_RS09830 (K0E64_09830) 2004322..2004981 - 660 WP_002911407.1 exodeoxyribonuclease X -
K0E64_RS09835 (K0E64_09835) 2005060..2005290 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K0E64_RS09840 (K0E64_09840) 2005403..2005777 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K0E64_RS09845 (K0E64_09845) 2005781..2006650 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K0E64_RS09850 (K0E64_09850) 2006667..2007005 + 339 WP_211589099.1 YebY family protein -
- 2007128..2007273 - 146 - - Antitoxin
- 2007164..2007266 + 103 - - Toxin
K0E64_RS09855 (K0E64_09855) 2007641..2007784 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K0E64_RS09860 (K0E64_09860) 2007889..2008857 - 969 WP_004151446.1 VirK/YbjX family protein -
K0E64_RS09865 (K0E64_09865) 2009014..2009667 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K0E64_RS09870 (K0E64_09870) 2009664..2009855 - 192 WP_002911395.1 YebW family protein -
K0E64_RS09875 (K0E64_09875) 2009953..2010192 - 240 WP_002911393.1 YebV family protein -
K0E64_RS09880 (K0E64_09880) 2010308..2011741 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T211619 NZ_CP080297:2007164-2007266 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT211619 NZ_CP080297:c2007273-2007128 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References