Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1686726..1686960 | Replicon | chromosome |
| Accession | NZ_CP080139 | ||
| Organism | Escherichia coli strain PK8241 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1686727..1686830 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1686726..1686960 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZY05_RS08825 | 1683924..1684733 | + | 810 | WP_219788448.1 | recombination protein RecT | - |
| KZY05_RS08830 | 1684790..1684984 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| KZY05_RS08835 | 1684977..1685165 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1684983..1685161 | - | 179 | NuclAT_1 | - | - |
| - | 1684983..1685161 | - | 179 | NuclAT_1 | - | - |
| - | 1684983..1685161 | - | 179 | NuclAT_1 | - | - |
| - | 1684983..1685161 | - | 179 | NuclAT_1 | - | - |
| KZY05_RS08840 | 1685272..1685553 | + | 282 | WP_001311878.1 | excisionase | - |
| KZY05_RS08845 | 1685519..1686595 | + | 1077 | WP_033544538.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1686726..1686960 | + | 235 | - | - | Antitoxin |
| - | 1686727..1686830 | - | 104 | - | - | Toxin |
| KZY05_RS08850 | 1686987..1687328 | - | 342 | WP_000976472.1 | YebY family protein | - |
| KZY05_RS08855 | 1687341..1688213 | - | 873 | WP_069722788.1 | copper homeostasis membrane protein CopD | - |
| KZY05_RS08860 | 1688217..1688591 | - | 375 | WP_000255065.1 | CopC domain-containing protein YobA | - |
| KZY05_RS08865 | 1688730..1688960 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| KZY05_RS08870 | 1689062..1689718 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| KZY05_RS08875 | 1689742..1690404 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1628824..1694369 | 65545 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T211024 NZ_CP080139:c1686830-1686727 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT211024 NZ_CP080139:1686726-1686960 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
