Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1993530..1993801 Replicon chromosome
Accession NZ_CP080133
Organism Escherichia coli strain PK8277

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1993660..1993763 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1993530..1993801 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZY04_RS09570 1990085..1990747 - 663 WP_000944256.1 exodeoxyribonuclease X -
KZY04_RS09575 1990771..1991427 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
KZY04_RS09580 1991529..1991759 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KZY04_RS09585 1991898..1992272 + 375 WP_000255065.1 CopC domain-containing protein YobA -
KZY04_RS09590 1992276..1993148 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
KZY04_RS09595 1993161..1993502 + 342 WP_000976472.1 YebY family protein -
- 1993530..1993801 - 272 - - Antitoxin
- 1993660..1993763 + 104 - - Toxin
KZY04_RS09600 1993898..1994554 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
KZY04_RS09605 1994555..1994746 - 192 WP_001313035.1 YebW family protein -
KZY04_RS09610 1994851..1995087 - 237 WP_001295499.1 YebV family protein -
KZY04_RS09615 1995205..1996644 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1956640..2009639 52999


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T210997 NZ_CP080133:1993660-1993763 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT210997 NZ_CP080133:c1993801-1993530 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References