Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2400149..2400417 Replicon chromosome
Accession NZ_CP080120
Organism Escherichia coli strain M24

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2400277..2400379 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2400149..2400417 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZX72_RS11450 2396702..2397364 - 663 WP_000944256.1 exodeoxyribonuclease X -
KZX72_RS11455 2397388..2398044 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
KZX72_RS11460 2398146..2398376 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KZX72_RS11465 2398515..2398889 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KZX72_RS11470 2398893..2399765 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
KZX72_RS11475 2399778..2400119 + 342 WP_000976472.1 YebY family protein -
- 2400149..2400417 - 269 - - Antitoxin
- 2400277..2400379 + 103 - - Toxin
KZX72_RS11480 2400514..2401170 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
KZX72_RS11485 2401171..2401362 - 192 WP_001296140.1 YebW family protein -
KZX72_RS11490 2401467..2401703 - 237 WP_001295499.1 YebV family protein -
KZX72_RS11495 2401820..2403259 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T210911 NZ_CP080120:2400277-2400379 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT210911 NZ_CP080120:c2400417-2400149 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References