Detailed information of TA system TA210432

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 453251..453904
• Replicon: chromosome
• Accession: NZ_CP079942
• Organism: Acinetobacter baumannii strain B10

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: KZH52_RS02210
• Protein ID: WP_000607077.1
• Coordinates: 453515..453904 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: KZH52_RS02205
• Protein ID: WP_001288210.1
• Coordinates: 453251..453508 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KZH52_RS02185 (KZH52_02185)	448767..449774	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
KZH52_RS02190 (KZH52_02190)	449793..450170	+	378	WP_001216380.1	50S ribosomal protein L17	-
KZH52_RS02195 (KZH52_02195)	450352..451842	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
KZH52_RS02200 (KZH52_02200)	451891..453063	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
KZH52_RS02205 (KZH52_02205)	453251..453508	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
KZH52_RS02210 (KZH52_02210)	453515..453904	+	390	WP_000607077.1	membrane protein	Toxin
KZH52_RS02215 (KZH52_02215)	454674..455759	+	1086	WP_000049106.1	hypothetical protein	-
KZH52_RS02220 (KZH52_02220)	455837..456403	+	567	WP_000651538.1	rhombosortase	-
KZH52_RS02225 (KZH52_02225)	456591..458786	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T210432 WP_000607077.1 NZ_CP079942:453515-453904 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T210432 NZ_CP104521:2091972-2092148 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTAAATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT210432 WP_001288210.1 NZ_CP079942:453251-453508 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT210432 NZ_CP104521:2092192-2092608 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACTCCTGCGCCGGAAGGCGGTTATGTGGTTTCTTTTGTAGATATCCCTGAAGCGTTGAC
GCAGGGAGAAACTGTTGCTGAAGCGATGGAAGCAGCAAAAGATGCCTTACTCACCGCATTTGATTTTTATTTTGAAGATA
ATGAGCTAATCCCGTTGCCTTCGCCATTAACTAACAACGATCACTTTATTGAAGTGCCTTTAAGTATCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGACGAATTGGCAAACCTAAACAGGAGAT
TACTCGCTTATTTAACTTGCACCATGCTACAAAAATCGACGCCGTCCAGCTTGCGGCTAAGGCGCTTGGCAAAGAGTTAT
CACTGGTGATGGTTTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7