Detailed information of TA system TA210207

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 190076..190334
• Replicon: chromosome
• Accession: NZ_CP079838
• Organism: Salmonella enterica subsp. salamae strain LHICA_SA3

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: -
• Locus tag: JMJ83_RS00895
• Protein ID: WP_001135702.1
• Coordinates: 190182..190334 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	190076..190131 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JMJ83_RS00875	185260..186255	-	996	WP_079815085.1	acyltransferase	-
JMJ83_RS00880	186421..186723	+	303	WP_219190709.1	YsaB family lipoprotein	-
JMJ83_RS00885	186862..187773	+	912	WP_001168556.1	glycine--tRNA ligase subunit alpha	-
JMJ83_RS00890	187783..189852	+	2070	WP_079974321.1	glycine--tRNA ligase subunit beta	-
-	190076..190131	-	56	-	-	Antitoxin
JMJ83_RS00895	190182..190334	+	153	WP_001135702.1	type I toxin-antitoxin system toxin HokA	Toxin
JMJ83_RS00900	190460..190999	-	540	WP_046093855.1	copper-binding periplasmic metallochaperone CueP	-
JMJ83_RS00905	191172..191384	-	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
JMJ83_RS00910	191672..191962	-	291	WP_000455790.1	HTH-type transcriptional regulator	-
JMJ83_RS00915	192400..193110	+	711	WP_000190525.1	DUF3053 domain-containing protein	-
JMJ83_RS00920	193160..194134	-	975	WP_219175825.1	glyoxylate/hydroxypyruvate reductase GhrB	-
JMJ83_RS00925	194352..195014	-	663	WP_000747548.1	OmpA family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5650.73 Da
• Isoelectric Point: 6.9149

>T210207 WP_001135702.1 NZ_CP079838:190182-190334 [Salmonella enterica subsp. salamae]
MPQKGMLYSLIVICLTILLFTWIVRDSLCELHIRQGNNELAASLACDSKQ

Nucleotide

• Length: 153 bp

>T210207 NZ_CP104472:c853820-853569 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT210207 NZ_CP079838:c190131-190076 [Salmonella enterica subsp. salamae]
GTTCAAGCATAGAGGTGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin