Detailed information of TA system TA209776

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 4511477..4512002
• Replicon: chromosome
• Accession: NZ_CP079716
• Organism: Pseudomonas amygdali strain HS1

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: KXJ79_RS19560
• Protein ID: WP_219169937.1
• Coordinates: 4511712..4512002 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KXJ79_RS19555
• Protein ID: WP_219169935.1
• Coordinates: 4511477..4511722 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KXJ79_RS19550 (KXJ79_19545)	4507391..4511302	-	3912	WP_054077974.1	ATP-dependent RNA helicase HrpA	-
KXJ79_RS19555 (KXJ79_19550)	4511477..4511722	+	246	WP_219169935.1	antitoxin	Antitoxin
KXJ79_RS19560 (KXJ79_19555)	4511712..4512002	+	291	WP_219169937.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KXJ79_RS19565 (KXJ79_19560)	4512099..4513790	-	1692	WP_058408531.1	long-chain-fatty-acid--CoA ligase FadD1	-
KXJ79_RS19570 (KXJ79_19565)	4514146..4515834	-	1689	WP_058400094.1	long-chain-fatty-acid--CoA ligase FadD2	-
KXJ79_RS19575 (KXJ79_19570)	4516203..4516673	+	471	WP_005743244.1	MaoC family dehydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10980.02 Da
• Isoelectric Point: 10.7963

>T209776 WP_219169937.1 NZ_CP079716:4511712-4512002 [Pseudomonas amygdali]
MTFKLEFLPSALKEWKKLGHTVRAQLKKKLLERLGLPRIAGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGAIYDAAKDRLPP

Nucleotide

• Length: 291 bp

>T209776 NZ_CP104309:309522-309797 [Escherichia coli O157:H7]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATATTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGTAAGC
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8827.22 Da
• Isoelectric Point: 4.5200

>AT209776 WP_219169935.1 NZ_CP079716:4511477-4511722 [Pseudomonas amygdali]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLADLIKSRQHEKPLSVDIDD
L

Nucleotide

• Length: 246 bp

>AT209776 NZ_CP104309:309794-310153 [Escherichia coli O157:H7]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA