Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1856169..1856403 Replicon chromosome
Accession NC_004741
Organism Shigella flexneri 2a str. 2457T

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1856170..1856273 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1856169..1856403 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S_RS10070 1852302..1852451 + 150 Protein_1841 transposase -
S_RS25855 1852484..1853694 - 1211 Protein_1842 IS3 family transposase -
S_RS10090 1853749..1854597 + 849 Protein_1843 IS3-like element IS600 family transposase -
S_RS25860 1854714..1854995 + 282 WP_005127484.1 excisionase -
S_RS28750 1854961..1856038 + 1078 Protein_1845 phage integrase Arm DNA-binding domain-containing protein -
- 1856169..1856403 + 235 - - Antitoxin
- 1856170..1856273 - 104 - - Toxin
S_RS10105 1856431..1856772 - 342 WP_000976476.1 YebY family protein -
S_RS25875 1856785..1857657 - 873 Protein_1847 copper homeostasis membrane protein CopD -
S_RS10120 1857661..1858035 - 375 WP_000168747.1 CopC domain-containing protein YobA -
S_RS10125 1858174..1858404 + 231 WP_000916763.1 DNA polymerase III subunit theta -
S_RS10130 1858506..1859162 + 657 Protein_1850 carbon-nitrogen hydrolase family protein -
S_RS10135 1859186..1859848 + 663 WP_000944268.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T20938 NC_004741:c1856273-1856170 [Shigella flexneri 2a str. 2457T]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT20938 NC_004741:1856169-1856403 [Shigella flexneri 2a str. 2457T]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References