Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2262551..2262719 Replicon chromosome
Accession NZ_CP078110
Organism Cronobacter sakazakii strain MOD1-H322

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2262554..2262657 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2262551..2262719 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTK77_RS10615 (BTK77_010615) 2257926..2259368 + 1443 WP_080320618.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BTK77_RS10620 (BTK77_010620) 2259481..2259720 + 240 WP_004386676.1 YebV family protein -
BTK77_RS10625 (BTK77_010625) 2259845..2260036 + 192 WP_004386675.1 YebW family protein -
BTK77_RS10630 (BTK77_010630) 2260037..2260681 - 645 WP_080320617.1 metallophosphoesterase -
BTK77_RS10635 (BTK77_010635) 2261040..2261132 - 93 WP_004386672.1 hypothetical protein -
BTK77_RS10640 (BTK77_010640) 2261478..2261813 - 336 WP_080320616.1 hypothetical protein -
BTK77_RS10645 (BTK77_010645) 2261767..2262327 - 561 WP_032968251.1 hypothetical protein -
- 2262551..2262719 + 169 - - Antitoxin
- 2262554..2262657 - 104 - - Toxin
BTK77_RS10650 (BTK77_010650) 2262796..2263134 - 339 WP_080320615.1 YebY family protein -
BTK77_RS10655 (BTK77_010655) 2263149..2264018 - 870 WP_080320614.1 copper homeostasis membrane protein CopD -
BTK77_RS10660 (BTK77_010660) 2264023..2264397 - 375 WP_007900668.1 CopC domain-containing protein YobA -
BTK77_RS10665 (BTK77_010665) 2264544..2264774 + 231 WP_007698883.1 DNA polymerase III subunit theta -
BTK77_RS10670 (BTK77_010670) 2264846..2265508 + 663 WP_007775901.1 exodeoxyribonuclease X -
BTK77_RS10675 (BTK77_010675) 2265505..2267568 - 2064 WP_080320613.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T208993 NZ_CP078110:c2262657-2262554 [Cronobacter sakazakii]
GGCAAGGCGACTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 169 bp

>AT208993 NZ_CP078110:2262551-2262719 [Cronobacter sakazakii]
GATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTCAGTCGCCTTGCCTTTTAAGAATAGATGACGACACCAGCTTTTCCAGTTTGCGGCTAAAGTCGCAG
CAAAAAGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References