Detailed information of TA system TA208909

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2969427..2970066
• Replicon: chromosome
• Accession: NZ_CP078018
• Organism: Acinetobacter junii strain AJ_351

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: EGT69_RS14150
• Protein ID: WP_039047468.1
• Coordinates: 2969427..2969822 (-)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A365PHJ6
• Locus tag: EGT69_RS14155
• Protein ID: WP_039047469.1
• Coordinates: 2969809..2970066 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGT69_RS14130 (EGT69_014130)	2964545..2966755	-	2211	WP_004683251.1	TRAP transporter large permease subunit	-
EGT69_RS14135 (EGT69_014135)	2966909..2967478	-	570	WP_004951830.1	rhombosortase	-
EGT69_RS14140 (EGT69_014140)	2967567..2968649	-	1083	WP_004683255.1	hypothetical protein	-
EGT69_RS14145 (EGT69_014145)	2969008..2969215	-	208	Protein_2761	hypothetical protein	-
EGT69_RS14150 (EGT69_014150)	2969427..2969822	-	396	WP_039047468.1	hypothetical protein	Toxin
EGT69_RS14155 (EGT69_014155)	2969809..2970066	-	258	WP_039047469.1	succinate dehydrogenase assembly factor 2	Antitoxin
EGT69_RS14160 (EGT69_014160)	2970251..2971423	+	1173	WP_125297281.1	acyl-CoA dehydrogenase family protein	-
EGT69_RS14165 (EGT69_014165)	2971471..2971971	-	501	WP_005403244.1	DUF2059 domain-containing protein	-
EGT69_RS14170 (EGT69_014170)	2972092..2973582	-	1491	WP_004909331.1	NAD(P)/FAD-dependent oxidoreductase	-
EGT69_RS14175 (EGT69_014175)	2973956..2974507	+	552	WP_125297282.1	hypothetical protein	-
EGT69_RS14180 (EGT69_014180)	2974622..2974987	-	366	WP_004641032.1	50S ribosomal protein L17	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 15453.33 Da
• Isoelectric Point: 7.6985

>T208909 WP_039047468.1 NZ_CP078018:c2969822-2969427 [Acinetobacter junii]
MYTAKRIFELQSSRFSLGLQLFCFLSINILLYQLLSAFLWLVCLLIMGWAGWSALNKPKINQIEYLCDDDWSIRFDGVEP
NIEQGKLLKIIDHHLYIVLHFSNIESKTCVIWWDQLSLNQWKMLKLLSKIA

Nucleotide

• Length: 396 bp

>T208909 NZ_CP103755:c4255336-4255052 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10116.64 Da
• Isoelectric Point: 4.5732

>AT208909 WP_039047469.1 NZ_CP078018:c2970066-2969809 [Acinetobacter junii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKQYYLTADPTEKALFAELVDQEDPDLLDWFMEVGEPPRAELKAFILKLK
KYVHG

Nucleotide

• Length: 258 bp

>AT208909 NZ_CP103755:c4255572-4255339 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Structures

Antitoxin

• AlphaFold DB: A0A365PHJ6