Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6119030..6119549 Replicon chromosome
Accession NC_004578
Organism Pseudomonas syringae pv. tomato str. DC3000

Toxin (Protein)


Gene name relE Uniprot ID Q87UB8
Locus tag PSPTO_RS27855 Protein ID WP_011105461.1
Coordinates 6119030..6119320 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag PSPTO_RS27860 Protein ID WP_002551444.1
Coordinates 6119310..6119549 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSPTO_RS27835 6115993..6116622 + 630 WP_011105458.1 NAD(P)H-dependent oxidoreductase -
PSPTO_RS27840 6116679..6117293 - 615 WP_005769904.1 histidine phosphatase family protein -
PSPTO_RS27845 6117371..6117712 - 342 WP_011105459.1 hypothetical protein -
PSPTO_RS27850 6118066..6118803 + 738 WP_011105460.1 hypothetical protein -
PSPTO_RS27855 6119030..6119320 - 291 WP_011105461.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSPTO_RS27860 6119310..6119549 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PSPTO_RS27865 6119724..6120185 - 462 WP_011105462.1 GNAT family N-acetyltransferase -
PSPTO_RS27870 6120558..6121052 + 495 WP_010209025.1 hypothetical protein -
PSPTO_RS27875 6121092..6122366 - 1275 WP_011105463.1 OprD family porin -
PSPTO_RS27880 6122596..6122802 - 207 WP_057443202.1 hypothetical protein -
PSPTO_RS27885 6123022..6124128 - 1107 WP_011105465.1 agmatine deiminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11195.05 Da        Isoelectric Point: 10.2579

>T20883 WP_011105461.1 NC_004578:c6119320-6119030 [Pseudomonas syringae pv. tomato str. DC3000]
MTYSLEFDARALKEWRKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLSG

Download         Length: 291 bp

>T20883 NC_004578:c6119320-6119030 [Pseudomonas syringae pv. tomato str. DC3000]
ATGACTTATAGCCTCGAGTTTGATGCGCGAGCTCTGAAGGAGTGGCGCAAATTAGGGGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCACCGCGCGTTGAAGCAAATCGTCTGCATGCGTTGCCCGACTGCTACAAAATCA
AACTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGAGTGGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT20883 WP_002551444.1 NC_004578:c6119549-6119310 [Pseudomonas syringae pv. tomato str. DC3000]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT20883 NC_004578:c6119549-6119310 [Pseudomonas syringae pv. tomato str. DC3000]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAAGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACTCC
TTCGGAATTGCTGCGTCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGCTACCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCGTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q87UB8

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References