Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4143187..4143700 Replicon chromosome
Accession NC_004578
Organism Pseudomonas syringae pv. tomato str. DC3000

Toxin (Protein)


Gene name relE Uniprot ID Q87YW5
Locus tag PSPTO_RS19015 Protein ID WP_011104666.1
Coordinates 4143416..4143700 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UR83
Locus tag PSPTO_RS19010 Protein ID WP_005740683.1
Coordinates 4143187..4143426 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSPTO_RS18990 4139347..4140132 + 786 WP_005765329.1 membrane protein -
PSPTO_RS18995 4140274..4141182 - 909 WP_011104663.1 DUF808 domain-containing protein -
PSPTO_RS19000 4141330..4141836 - 507 WP_046463288.1 winged helix-turn-helix transcriptional regulator -
PSPTO_RS19005 4142002..4143018 + 1017 WP_003376162.1 1-aminocyclopropane-1-carboxylate deaminase -
PSPTO_RS19010 4143187..4143426 + 240 WP_005740683.1 ribbon-helix-helix protein, CopG family Antitoxin
PSPTO_RS19015 4143416..4143700 + 285 WP_011104666.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSPTO_RS19020 4143736..4144590 - 855 WP_011104667.1 LysR family transcriptional regulator -
PSPTO_RS19025 4144665..4145597 + 933 WP_011104668.1 DMT family transporter -
PSPTO_RS19030 4145626..4147554 - 1929 WP_044390209.1 methyl-accepting chemotaxis protein -
PSPTO_RS19035 4147806..4148291 - 486 WP_007245243.1 DUF2269 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10838.62 Da        Isoelectric Point: 10.0884

>T20882 WP_011104666.1 NC_004578:4143416-4143700 [Pseudomonas syringae pv. tomato str. DC3000]
MQVEWLKTALKNLDDEAAYISLENPAAAVAFVEALQISVKQLASFPALGREGRIAGTREWPLPDWPYLIPYRIRNGRLQV
LRIFHTRRQPPLVW

Download         Length: 285 bp

>T20882 NC_004578:4143416-4143700 [Pseudomonas syringae pv. tomato str. DC3000]
ATGCAGGTTGAATGGCTAAAAACAGCATTAAAAAACCTGGATGATGAAGCCGCCTACATCTCGCTAGAAAATCCGGCTGC
TGCGGTTGCTTTCGTAGAAGCACTACAAATAAGCGTAAAGCAGCTCGCAAGCTTTCCGGCCCTAGGCCGAGAGGGACGAA
TTGCTGGCACCAGAGAATGGCCTTTGCCAGACTGGCCTTACCTGATTCCATACCGCATCCGTAACGGCCGATTACAGGTT
CTGCGGATTTTCCACACGAGAAGGCAGCCGCCGTTGGTGTGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8753.90 Da        Isoelectric Point: 4.5822

>AT20882 WP_005740683.1 NC_004578:4143187-4143426 [Pseudomonas syringae pv. tomato str. DC3000]
MSVMSLRLPDEMADTLAHLAKATGRSKSFLALNALREYLTREAWQIAEIQRAIEEADAGEFASEEDVKAVMNKWANNAG

Download         Length: 240 bp

>AT20882 NC_004578:4143187-4143426 [Pseudomonas syringae pv. tomato str. DC3000]
ATGTCCGTTATGTCTCTACGCCTGCCGGACGAGATGGCAGATACCCTTGCACACCTCGCCAAAGCGACCGGCCGCAGCAA
GTCGTTTTTGGCCTTGAACGCATTACGTGAATACTTGACTCGCGAAGCCTGGCAGATTGCCGAAATTCAGCGTGCAATTG
AAGAAGCAGACGCGGGCGAGTTCGCAAGTGAAGAAGATGTAAAGGCAGTGATGAATAAATGGGCGAACAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q87YW5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M7Q4

References