Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3161133..3161278 Replicon chromosome
Accession NZ_CP077820
Organism Klebsiella pneumoniae strain FF1013

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3161140..3161242 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3161133..3161278 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU668_RS15335 3156665..3158098 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KU668_RS15340 3158214..3158453 + 240 WP_002911393.1 YebV family protein -
KU668_RS15345 3158551..3158742 + 192 WP_002911395.1 YebW family protein -
KU668_RS15350 3158739..3159392 - 654 WP_004175436.1 protein-serine/threonine phosphatase -
KU668_RS15355 3159549..3160517 + 969 WP_004151446.1 VirK/YbjX family protein -
KU668_RS15360 3160622..3160765 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3161133..3161278 + 146 - - Antitoxin
- 3161140..3161242 - 103 - - Toxin
KU668_RS15365 3161401..3161739 - 339 WP_002911404.1 YebY family protein -
KU668_RS15370 3161756..3162625 - 870 WP_023282759.1 copper homeostasis membrane protein CopD -
KU668_RS15375 3162629..3163003 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KU668_RS15380 3163116..3163346 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KU668_RS15385 3163425..3164084 + 660 WP_021440386.1 exodeoxyribonuclease X -
KU668_RS15390 3164088..3166148 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207996 NZ_CP077820:c3161242-3161140 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207996 NZ_CP077820:3161133-3161278 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References