Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4648305..4648450 Replicon chromosome
Accession NZ_CP077814
Organism Klebsiella pneumoniae strain FF1076

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4648312..4648414 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4648305..4648450 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU667_RS22720 (KU667_22630) 4643837..4645270 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KU667_RS22725 (KU667_22635) 4645386..4645625 + 240 WP_002911393.1 YebV family protein -
KU667_RS22730 (KU667_22640) 4645723..4645914 + 192 WP_002911395.1 YebW family protein -
KU667_RS22735 (KU667_22645) 4645911..4646564 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
KU667_RS22740 (KU667_22650) 4646721..4647689 + 969 WP_004151446.1 VirK/YbjX family protein -
KU667_RS22745 (KU667_22655) 4647794..4647937 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4648305..4648450 + 146 - - Antitoxin
- 4648312..4648414 - 103 - - Toxin
KU667_RS22750 (KU667_22660) 4648573..4648911 - 339 WP_002911404.1 YebY family protein -
KU667_RS22755 (KU667_22665) 4648928..4649797 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KU667_RS22760 (KU667_22670) 4649801..4650175 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KU667_RS22765 (KU667_22675) 4650288..4650518 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KU667_RS22770 (KU667_22680) 4650597..4651256 + 660 WP_002911407.1 exodeoxyribonuclease X -
KU667_RS22775 (KU667_22685) 4651260..4653320 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207939 NZ_CP077814:c4648414-4648312 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207939 NZ_CP077814:4648305-4648450 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References