Detailed information of TA system TA207735

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 1362579..1362980
• Replicon: chromosome
• Accession: NZ_CP077760
• Organism: Salmonella enterica subsp. enterica serovar Gallinarum strain 07Q015

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: KTV86_RS23270
• Protein ID: WP_023209683.1
• Coordinates: 1362852..1362980 (+)
• Length: 43 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	1362579..1362930 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KTV86_RS06690	1358112..1358477	-	366	WP_223671802.1	hypothetical protein	-
KTV86_RS06695	1359099..1359803	-	705	Protein_1317	integrase core domain-containing protein	-
KTV86_RS06700	1359856..1360104	+	249	WP_001675092.1	SymE family type I addiction module toxin	-
KTV86_RS06705	1360236..1360514	-	279	WP_001575647.1	hypothetical protein	-
KTV86_RS06710	1360900..1361298	-	399	WP_000828181.1	hypothetical protein	-
KTV86_RS06715	1362169..1362402	-	234	WP_124084119.1	hypothetical protein	-
-	1362579..1362930	-	352	-	-	Antitoxin
KTV86_RS23270	1362852..1362980	+	129	WP_023209683.1	hypothetical protein	Toxin
KTV86_RS06725	1363063..1363383	-	321	WP_223201872.1	Imm8 family immunity protein	-
KTV86_RS06730	1364163..1364528	-	366	WP_001231281.1	hypothetical protein	-
KTV86_RS06735	1364494..1367294	-	2801	Protein_1325	RHS repeat-associated core domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1350127..1388132	38005
	-	flank	IS/Tn	-	-	1359099..1359380	281

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 43 a.a.
• Molecular weight: 4492.16 Da
• Isoelectric Point: 4.4551

>T207735 WP_023209683.1 NZ_CP077760:1362852-1362980 [Salmonella enterica subsp. enterica serovar Gallinarum]
VKISDGCIVLMADGNEVQELREQLYQAKRVVKGGEGCAGLVD

Nucleotide

• Length: 129 bp

>T207735 NZ_CP103499:4050907-4051125 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin

Nucleotide

• Length: 352 bp

>AT207735 NZ_CP077760:c1362930-1362579 [Salmonella enterica subsp. enterica serovar Gallinarum]
CCTGATAAAGCTGTTCGCGCAGCTCCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCTTCACC
GTCACGCCGCTCCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGC
AGGTTTCGCTGTTGATGTGGCGGACGCTGGCGCCGGAGGTATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCC
GGATGCTGGCTGATTGTGGAGCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCCCCTCTCCCCGGCCAG
TGATGAGCAACCGGCTACCGGGGCCGTATTTT

Structures

Antitoxin