Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 77175..77780 Replicon chromosome
Accession NZ_CP077075
Organism Pseudomonas xanthosomae strain COR54

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag KSS93_RS00335 Protein ID WP_217886695.1
Coordinates 77490..77780 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KSS93_RS00330 Protein ID WP_217886694.1
Coordinates 77175..77480 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS93_RS00310 (KSS93_00310) 73305..75557 + 2253 WP_217886693.1 AsmA family protein -
KSS93_RS00315 (KSS93_00315) 75554..76621 + 1068 WP_217841376.1 A/G-specific adenine glycosylase -
KSS93_RS00320 (KSS93_00320) 76618..76890 + 273 WP_217841375.1 oxidative damage protection protein -
KSS93_RS00330 (KSS93_00330) 77175..77480 - 306 WP_217886694.1 putative addiction module antidote protein Antitoxin
KSS93_RS00335 (KSS93_00335) 77490..77780 - 291 WP_217886695.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS93_RS00340 (KSS93_00340) 77943..78935 + 993 WP_225917275.1 polyphosphate kinase 2 -
KSS93_RS00345 (KSS93_00345) 79079..79522 + 444 WP_217886696.1 hypothetical protein -
KSS93_RS00350 (KSS93_00350) 79700..81085 - 1386 WP_217886697.1 GABA permease -
KSS93_RS00355 (KSS93_00355) 81707..82480 + 774 WP_217886698.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10833.53 Da        Isoelectric Point: 10.2398

>T206632 WP_217886695.1 NZ_CP077075:c77780-77490 [Pseudomonas xanthosomae]
MHTLIQTDRYMRWFAALRDARAQARINVRLRRVELGALGDCKSVGEGVFELRIDYGPGYRVYCVQRGHEVIILLAGGDKS
SQTRDIKSALALARNV

Download         Length: 291 bp

>T206632 NZ_CP102536:1231374-1231667 [Bifidobacterium breve]
ATGCTCAAACCGGATTACACGGCGGCATTCCAGCGAGATATCAAGAAACTCAAACGCAAGCACACTGATTTACGCCCGCT
GAAAGAAGTCATTCGTCTGGTGCTTGAGGACACGGCGGACTCCAAGGAAGCATTGAGGCGTAGGCATCGAGCCCACACAC
TTACCGGTGATCTAAACGGCGTACTGGAATGCCACATCGGCAATGCCGGCGACTGGCTGCTTCTATGGATTCGCGATGAT
GGTACCGCCATGTTCATGCGAACCGGCAGCCATGACGAACTGTTGGGCAAATAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10745.38 Da        Isoelectric Point: 5.0877

>AT206632 WP_217886694.1 NZ_CP077075:c77480-77175 [Pseudomonas xanthosomae]
MTDVKLSRWDAADHLKTEQDMALYLEACLEENDPALLAAALGDIARARGMAQLARDTGLTREGLYKALSADGNPSLATIM
KVMAALGVRLHAEVVPPRAAG

Download         Length: 306 bp

>AT206632 NZ_CP102536:1231101-1231370 [Bifidobacterium breve]
GTGAGCATGGCATCCGTCACAGTCCGCGTGGATGCGGACACCAAGCAGAAAGCCGCAAACATAGCCGAGGATCTCGGTCT
GGACTTGTCTTCGGTCACCCGCGCCTTCTACAAGCAGATTGTCCGGGAGAGGCGCATTCCCCTAAACCTTTCCTATACGA
CCGTGCCGCCTGAAACCATGGAGGCCCTTGACGAGGCGAAGAACAGGCTCGCCGACGGCCAACCTCGCTTCAACAGTGCC
GATGAGATGTTCGATTCGTTGGGAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References