Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 4305987..4306570 Replicon chromosome
Accession NZ_CP076723
Organism Geomonas oryzisoli strain RG10

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag KP004_RS18670 Protein ID WP_216799908.1
Coordinates 4306226..4306570 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag KP004_RS18665 Protein ID WP_216799907.1
Coordinates 4305987..4306229 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP004_RS18640 (KP004_18640) 4301820..4302644 - 825 WP_239026859.1 A/G-specific adenine glycosylase -
KP004_RS18645 (KP004_18645) 4302850..4303206 + 357 WP_199390309.1 TRL domain-containing protein -
KP004_RS18650 (KP004_18650) 4303625..4304485 + 861 WP_216799904.1 DMT family transporter -
KP004_RS18655 (KP004_18655) 4304632..4304850 + 219 WP_216799905.1 hypothetical protein -
KP004_RS18660 (KP004_18660) 4304979..4305908 + 930 WP_216799906.1 cation diffusion facilitator family transporter -
KP004_RS18665 (KP004_18665) 4305987..4306229 + 243 WP_216799907.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
KP004_RS18670 (KP004_18670) 4306226..4306570 + 345 WP_216799908.1 endoribonuclease MazF Toxin
KP004_RS18675 (KP004_18675) 4306586..4307179 - 594 WP_216799909.1 TetR/AcrR family transcriptional regulator -
KP004_RS18680 (KP004_18680) 4307385..4308947 + 1563 WP_216799910.1 acetyl-CoA hydrolase/transferase C-terminal domain-containing protein -
KP004_RS18685 (KP004_18685) 4309171..4309359 + 189 WP_216799911.1 hypothetical protein -
KP004_RS18690 (KP004_18690) 4309411..4310130 + 720 WP_216799912.1 DUF3108 domain-containing protein -
KP004_RS18695 (KP004_18695) 4310240..4310854 + 615 WP_216799913.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-111)

Antitoxin

SpoVT-AbrB domain

(6-47)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12638.64 Da        Isoelectric Point: 9.1223

>T206453 WP_216799908.1 NZ_CP076723:4306226-4306570 [Geomonas oryzisoli]
MTAMGYVPDRGEVVWLDFDPQAGHEHAGRRPAFVLSPRNYNKKTSLMLCCPITSQVKGYPFEVAVAGVTTVRGVILADQV
KSLDWQVRRAEKGGRASREVLEEVILKVRAILEG

Download         Length: 345 bp

>T206453 NZ_CP102434:1352219-1352473 [Vibrio parahaemolyticus]
ATGAGAATCGTATCTTTTACTGAAGCTAGAAATGGTCTCAAAGCTGTTTTAGACGGTGTAGTTAATGATGCTGATACAAC
AGTTATTACACGCCGTGATTCTGAGGATGCAGTGGTTATGTCTTTAGACTACTACAATAGCCTTATGGAGACTGTTCATT
TACTACGCTCTCCTCAAAACGTTGAACACCTAAACCGTTCGATAGCACAGTACCGCGCTGGTAAAACAACAGCACGAGAG
TTAATTGATGAGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8567.86 Da        Isoelectric Point: 5.0506

>AT206453 WP_216799907.1 NZ_CP076723:4305987-4306229 [Geomonas oryzisoli]
MVAKAQKWGNSLAVRLPKSIAAECGIEADSPVEITRQEGYIVIKPIVNKGLSLDALLDGINEENLHSEVSSGKPVGRELL

Download         Length: 243 bp

>AT206453 NZ_CP102434:1352466-1352735 [Vibrio parahaemolyticus]
ATGAGTAGTAGTCAACGTTTATTATCGTGGACTGATGATGCTTGGGATGACTACCTGTATTGGCAAACTCAAGACAAGAA
AACACTCAAGCGCATCAATAAACTCATCAATGATGTTAAGCGCTCTCCATTTGAGGGCATTGGTAAACCAGAGCCGTTAA
AAGAGAACTTATCTGGTTTTTGGTCTCGTCGTATTGATGATACTAATAGGCTTGTTTACGCAGTCGATGATCAAGCGATA
ACGATAATTTCATGTCGTTACCACTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References