Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2704317..2704575 Replicon chromosome
Accession NZ_CP076595
Organism Erwinia amylovora isolate CP20130202

Toxin (Protein)


Gene name hok Uniprot ID -
Locus tag KQH34_RS12425 Protein ID WP_231840709.1
Coordinates 2704477..2704575 (+) Length 33 a.a.

Antitoxin (RNA)


Gene name sok
Locus tag -
Coordinates 2704317..2704363 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQH34_RS12380 (KQH34_12350) 2699763..2699906 - 144 WP_004160049.1 hypothetical protein -
KQH34_RS12385 (KQH34_12355) 2700379..2700771 - 393 WP_004160048.1 DoxX family protein -
KQH34_RS12390 (KQH34_12360) 2700981..2701262 - 282 WP_004160039.1 YqjK-like family protein -
KQH34_RS12395 (KQH34_12365) 2701262..2701654 - 393 WP_004160038.1 phage holin family protein -
KQH34_RS12400 (KQH34_12370) 2701656..2701961 - 306 WP_004160037.1 DUF883 family protein -
KQH34_RS12405 (KQH34_12375) 2702004..2702375 - 372 WP_004160036.1 DUF1090 domain-containing protein -
KQH34_RS12410 (KQH34_12380) 2702543..2702935 - 393 WP_004160035.1 EnvZ/OmpR regulon moderator MzrA -
KQH34_RS12415 (KQH34_12385) 2702932..2703606 - 675 WP_004160034.1 DedA family protein -
- 2704317..2704363 - 47 - - Antitoxin
KQH34_RS12425 2704477..2704575 + 99 WP_231840709.1 Hok/Gef family protein Toxin
KQH34_RS12430 (KQH34_12395) 2704719..2705951 - 1233 WP_004160030.1 serine/threonine transporter SstT -
KQH34_RS12435 (KQH34_12400) 2706186..2707166 - 981 WP_013035818.1 TerC family protein -
KQH34_RS12440 (KQH34_12405) 2707579..2709270 + 1692 WP_004160025.1 chloride channel protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(2-28)


Sequences

Toxin        


Download         Length: 33 a.a.        Molecular weight: 3810.40 Da        Isoelectric Point: 8.9407

>T206018 WP_231840709.1 NZ_CP076595:2704477-2704575 [Erwinia amylovora]
IFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Download         Length: 99 bp

>T206018 NZ_CP102070:c306190-306095 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 47 bp

>AT206018 NZ_CP076595:c2704363-2704317 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References