Detailed information of TA system TA205988

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3083828..3084086
• Replicon: chromosome
• Accession: NZ_CP076591
• Organism: Erwinia amylovora isolate CP201142

Toxin (Protein)

• Gene name: hok
• Uniprot ID: -
• Locus tag: KQH37_RS14045
• Protein ID: WP_231840709.1
• Coordinates: 3083988..3084086 (+)
• Length: 33 a.a.

Antitoxin (RNA)

Gene name	sok
Locus tag	-
Coordinates	3083828..3083874 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQH37_RS14000 (KQH37_13990)	3079274..3079417	-	144	WP_004160049.1	hypothetical protein	-
KQH37_RS14005 (KQH37_13995)	3079890..3080282	-	393	WP_004160048.1	DoxX family protein	-
KQH37_RS14010 (KQH37_14000)	3080492..3080773	-	282	WP_004160039.1	YqjK-like family protein	-
KQH37_RS14015 (KQH37_14005)	3080773..3081165	-	393	WP_004160038.1	phage holin family protein	-
KQH37_RS14020 (KQH37_14010)	3081167..3081472	-	306	WP_004160037.1	DUF883 family protein	-
KQH37_RS14025 (KQH37_14015)	3081515..3081886	-	372	WP_004160036.1	DUF1090 domain-containing protein	-
KQH37_RS14030 (KQH37_14020)	3082054..3082446	-	393	WP_004160035.1	EnvZ/OmpR regulon moderator MzrA	-
KQH37_RS14035 (KQH37_14025)	3082443..3083117	-	675	WP_004160034.1	DedA family protein	-
-	3083828..3083874	-	47	-	-	Antitoxin
KQH37_RS14045	3083988..3084086	+	99	WP_231840709.1	Hok/Gef family protein	Toxin
KQH37_RS14050 (KQH37_14035)	3084230..3085462	-	1233	WP_004160030.1	serine/threonine transporter SstT	-
KQH37_RS14055 (KQH37_14040)	3085697..3086677	-	981	WP_013035818.1	TerC family protein	-
KQH37_RS14060 (KQH37_14045)	3087090..3088781	+	1692	WP_004160025.1	chloride channel protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (2-28)

Sequences

Toxin

Protein

• Length: 33 a.a.
• Molecular weight: 3810.40 Da
• Isoelectric Point: 8.9407

>T205988 WP_231840709.1 NZ_CP076591:3083988-3084086 [Erwinia amylovora]
IFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Nucleotide

• Length: 99 bp

>T205988 NZ_CP102061:814182-814556 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCAGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin

Nucleotide

• Length: 47 bp

>AT205988 NZ_CP076591:c3083874-3083828 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Structures

Antitoxin