Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2133781..2134052 Replicon chromosome
Accession NZ_CP076272
Organism Escherichia coli strain E21845/O/A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2133819..2133922 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2133781..2134052 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7A11_RS10545 2130938..2132377 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A7A11_RS10550 2132495..2132731 + 237 WP_001295499.1 YebV family protein -
A7A11_RS10555 2132836..2133027 + 192 WP_001296140.1 YebW family protein -
A7A11_RS10560 2133028..2133684 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2133781..2134052 + 272 - - Antitoxin
- 2133819..2133922 - 104 - - Toxin
A7A11_RS10565 2134080..2134421 - 342 WP_000976472.1 YebY family protein -
A7A11_RS10570 2134434..2135306 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
A7A11_RS10575 2135310..2135684 - 375 WP_000204700.1 CopC domain-containing protein YobA -
A7A11_RS10580 2135823..2136053 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A7A11_RS10585 2136155..2136811 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
A7A11_RS10590 2136835..2137497 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T205195 NZ_CP076272:c2133922-2133819 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT205195 NZ_CP076272:2133781-2134052 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References