Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2102491..2102762 Replicon chromosome
Accession NZ_CP076262
Organism Escherichia coli strain 0-4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2102529..2102632 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2102491..2102762 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7A18_RS10240 2099648..2101087 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A7A18_RS10245 2101205..2101441 + 237 WP_001295499.1 YebV family protein -
A7A18_RS10250 2101546..2101737 + 192 WP_001296140.1 YebW family protein -
A7A18_RS10255 2101738..2102394 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2102491..2102762 + 272 - - Antitoxin
- 2102529..2102632 - 104 - - Toxin
A7A18_RS10260 2102790..2103131 - 342 WP_000976472.1 YebY family protein -
A7A18_RS10265 2103144..2104016 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
A7A18_RS10270 2104020..2104394 - 375 WP_000204700.1 CopC domain-containing protein YobA -
A7A18_RS10275 2104533..2104763 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A7A18_RS10280 2104865..2105521 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
A7A18_RS10285 2105545..2106207 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T205064 NZ_CP076262:c2102632-2102529 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT205064 NZ_CP076262:2102491-2102762 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References