Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2359853..2360124 Replicon chromosome
Accession NZ_CP076241
Organism Escherichia coli O157:H7 strain Vac_07.1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2359983..2360086 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2359853..2360124 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKN65_RS12110 2356408..2357070 - 663 WP_000944244.1 exodeoxyribonuclease X -
JKN65_RS12115 2357094..2357750 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
JKN65_RS12120 2357852..2358082 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JKN65_RS12125 2358221..2358595 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JKN65_RS12130 2358599..2359471 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JKN65_RS12135 2359484..2359825 + 342 WP_000976483.1 YebY family protein -
- 2359853..2360124 - 272 - - Antitoxin
- 2359983..2360086 + 104 - - Toxin
JKN65_RS12140 2360221..2360877 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JKN65_RS12145 2360878..2361069 - 192 WP_001296140.1 YebW family protein -
JKN65_RS12150 2361174..2361410 - 237 WP_001295499.1 YebV family protein -
JKN65_RS12155 2361528..2362967 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2319829..2375965 56136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204907 NZ_CP076241:2359983-2360086 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204907 NZ_CP076241:c2360124-2359853 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References